2010 Louisville Cardinals Total Defense Split Stats through 01/10/2011
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 13 | 1876 | 2176 | 814 | 4052 | 4.98 | 311.7 |
| at Home | 7 | 947 | 1140 | 417 | 2087 | 5.00 | 298.1 |
| on Road/Neutral Site | 6 | 929 | 1036 | 397 | 1965 | 4.95 | 327.5 |
| in Wins | 7 | 859 | 1180 | 442 | 2039 | 4.61 | 291.3 |
| in Losses | 6 | 1017 | 996 | 372 | 2013 | 5.41 | 335.5 |
| vs. Conference | 7 | 968 | 1041 | 432 | 2009 | 4.65 | 287.0 |
| vs. Non-Conference | 6 | 908 | 1135 | 382 | 2043 | 5.35 | 340.5 |
| vs. Ranked (AP) | 0 | 0 | 0 | 0 | 0 | - | - |
| vs. Unranked (AP) | 13 | 1876 | 2176 | 814 | 4052 | 4.98 | 311.7 |
| vs. FBS (I-A) | 12 | 1784 | 2038 | 756 | 3822 | 5.06 | 318.5 |
| vs. FCS (I-AA) | 1 | 92 | 138 | 58 | 230 | 3.97 | 230.0 |
| vs. FBS Winning | 6 | 811 | 811 | 368 | 1622 | 4.41 | 270.3 |
| vs. FBS Non-Winning | 6 | 973 | 1227 | 388 | 2200 | 5.67 | 366.7 |
| vs. BCS AQ | 9 | 1375 | 1419 | 557 | 2794 | 5.02 | 310.4 |
| vs. BCS non-AQ | 3 | 409 | 619 | 199 | 1028 | 5.17 | 342.7 |
| in August/September | 3 | 499 | 516 | 183 | 1015 | 5.55 | 338.3 |
| in October | 5 | 657 | 878 | 292 | 1535 | 5.26 | 307.0 |
| in November | 4 | 550 | 556 | 265 | 1106 | 4.17 | 276.5 |
| in December/January | 1 | 170 | 226 | 74 | 396 | 5.35 | 396.0 |