2012 Conference USA Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/07/2013
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UCF | 1 | 256 | 155 | 75 | 411 | 5.48 | 411.0 |
| 2 | UTEP | 1 | 205 | 222 | 73 | 427 | 5.85 | 427.0 |
| 3 | Southern Mississippi | 3 | 571 | 640 | 206 | 1211 | 5.88 | 403.7 |
| 4 | SMU | 1 | 225 | 380 | 87 | 605 | 6.95 | 605.0 |
| 5 | East Carolina | 1 | 131 | 397 | 74 | 528 | 7.14 | 528.0 |
| 6 | UAB | 2 | 383 | 465 | 115 | 848 | 7.37 | 424.0 |