2021 Atlantic Coast Conference Leaders Total Offense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 8 | 1888 | 1865 | 533 | 3753 | 7.04 | 469.1 |
| 2 | Virginia | 8 | 848 | 3381 | 627 | 4229 | 6.74 | 528.6 |
| 3 | North Carolina | 9 | 1910 | 2158 | 634 | 4068 | 6.42 | 452.0 |
| 4 | Pittsburgh | 9 | 1339 | 3007 | 706 | 4346 | 6.16 | 482.9 |
| 5 | Virginia Tech | 8 | 1720 | 1375 | 508 | 3095 | 6.09 | 386.9 |
| 6 | Miami (Florida) | 8 | 896 | 2670 | 587 | 3566 | 6.07 | 445.8 |
| 7 | North Carolina State | 8 | 802 | 2388 | 538 | 3190 | 5.93 | 398.8 |
| 7 | Georgia Tech | 8 | 1372 | 1799 | 535 | 3171 | 5.93 | 396.4 |
| 9 | Wake Forest | 10 | 1594 | 3101 | 826 | 4695 | 5.68 | 469.5 |
| 10 | Florida State | 8 | 1159 | 1684 | 515 | 2843 | 5.52 | 355.4 |
| 11 | Syracuse | 8 | 1698 | 1131 | 520 | 2829 | 5.44 | 353.6 |
| 12 | Clemson | 8 | 1418 | 1412 | 533 | 2830 | 5.31 | 353.8 |
| 13 | Boston College | 8 | 1089 | 1415 | 524 | 2504 | 4.78 | 313.0 |
| 14 | Duke | 8 | 1173 | 1666 | 611 | 2839 | 4.65 | 354.9 |