2021 Pac-12 Conference Leaders Total Defense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | California | 9 | 1250 | 1800 | 606 | 3050 | 5.03 | 338.9 |
| 2 | Washington | 9 | 1803 | 1346 | 606 | 3149 | 5.20 | 349.9 |
| 3 | Arizona State | 9 | 1242 | 1966 | 620 | 3208 | 5.17 | 356.4 |
| 4 | Utah | 10 | 1103 | 2133 | 643 | 3236 | 5.03 | 323.6 |
| 5 | Washington State | 9 | 1384 | 1925 | 588 | 3309 | 5.63 | 367.7 |
| 6 | UCLA | 9 | 1303 | 2094 | 606 | 3397 | 5.61 | 377.4 |
| 7 | Arizona | 9 | 1608 | 1799 | 559 | 3407 | 6.09 | 378.6 |
| 8 | Oregon | 10 | 1338 | 2225 | 699 | 3563 | 5.10 | 356.3 |
| 9 | Oregon State | 9 | 1476 | 2130 | 595 | 3606 | 6.06 | 400.7 |
| 10 | USC | 9 | 1579 | 2105 | 557 | 3684 | 6.61 | 409.3 |
| 11 | Colorado | 9 | 1748 | 2317 | 635 | 4065 | 6.40 | 451.7 |
| 12 | Stanford | 9 | 2212 | 1943 | 634 | 4155 | 6.55 | 461.7 |