2021 Pac-12 Conference Leaders Total Defense - Games Lost Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oregon | 4 | 845 | 820 | 273 | 1665 | 6.10 | 416.3 |
| 2 | Utah | 4 | 805 | 974 | 267 | 1779 | 6.66 | 444.8 |
| 3 | Arizona State | 5 | 912 | 925 | 327 | 1837 | 5.62 | 367.4 |
| 4 | UCLA | 4 | 702 | 1216 | 277 | 1918 | 6.92 | 479.5 |
| 5 | Washington State | 6 | 1180 | 1246 | 422 | 2426 | 5.75 | 404.3 |
| 6 | Oregon State | 6 | 995 | 1692 | 430 | 2687 | 6.25 | 447.8 |
| 7 | California | 7 | 1231 | 1530 | 501 | 2761 | 5.51 | 394.4 |
| 8 | Washington | 8 | 1844 | 925 | 534 | 2769 | 5.19 | 346.1 |
| 9 | USC | 8 | 1610 | 1913 | 511 | 3523 | 6.89 | 440.4 |
| 10 | Colorado | 8 | 1737 | 1876 | 539 | 3613 | 6.70 | 451.6 |
| 11 | Stanford | 9 | 2168 | 2019 | 595 | 4187 | 7.04 | 465.2 |
| 12 | Arizona | 11 | 2127 | 2187 | 703 | 4314 | 6.14 | 392.2 |