2021 National Leaders Tackles For Loss - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Will Anderson Jr. | Alabama | SO | LB | 10 | 23.5 | 100 | 2.35 |
| 2 | Devin Lloyd | Utah | JR | LB | 9 | 18.0 | 86 | 2.00 |
| 3 | Leo Chenal | Wisconsin | JR | ILB | 8 | 15.5 | 83 | 1.94 |
| 4 | Cameron Thomas | SDSU | JR | DL | 12 | 19.5 | 76 | 1.63 |
| 5 | Yasir Abdullah | Louisville | JR | LB | 8 | 12.5 | 71 | 1.56 |
| 5 | Jermaine Johnson II | FSU | SR | DE | 8 | 12.5 | 69 | 1.56 |
| 7 | Nick Heninger | Utah State | SR | DE | 12 | 18.5 | 112 | 1.54 |
| 7 | Andre Carter II | Army | JR | OLB | 12 | 18.5 | 96 | 1.54 |
| 9 | Scott Patchan | CSU | SR | DL | 10 | 15.0 | 90 | 1.50 |
| 10 | Joey Noble | New Mexico | SR | DE | 10 | 14.5 | 44 | 1.45 |
| 11 | Jaxon Player | Tulsa | SR | DL | 9 | 13.0 | 41 | 1.44 |
| 12 | Kivon Bennett | Ark St | JR | DL | 11 | 15.5 | 66 | 1.41 |
| 13 | Sam Williams | Miss | SR | DL | 10 | 14.0 | 65 | 1.40 |
| 14 | Darius Hodges | Tulane | FR | JOK | 8 | 11.0 | 32 | 1.38 |
| 15 | Vince Sanford | Air Force | JR | OLB | 11 | 15.0 | 104 | 1.36 |
| 15 | Javon Solomon | Troy | FR | BAN | 11 | 15.0 | 75 | 1.36 |
| 17 | Leonard Taylor | Miami (Fl) | FR | DL | 7 | 9.5 | 19 | 1.36 |
| 18 | Brenton Cox Jr. | Florida | JR | OLB | 10 | 13.5 | 58 | 1.35 |
| 18 | Blaze Alldredge | Missouri | SR | LB | 10 | 13.5 | 54 | 1.35 |
| 18 | Carson Wells | Colorado | JR | OLB | 10 | 13.5 | 36 | 1.35 |
| 21 | Jordan Ferguson | MTSU | JR | DE | 13 | 17.5 | 80 | 1.35 |
| 22 | DQ Thomas | MTSU | SR | LB | 12 | 16.0 | 70 | 1.33 |
| 23 | Josh Paschal | Kentucky | SR | DE | 11 | 14.5 | 62 | 1.32 |
| 23 | Ralph Holley | W Mich | SR | DL | 11 | 14.5 | 55 | 1.32 |
| 25 | Troy Hairston II | CMU | SR | DL | 13 | 17.0 | 96 | 1.31 |
| 26 | D'Marco Jackson | App St | SR | ILB | 12 | 15.5 | 60 | 1.29 |
| 27 | Ali Fayad | W Mich | SR | DL | 11 | 14.0 | 68 | 1.27 |
| 27 | Rondell Bothroyd | Wk Forest | SO | DL | 11 | 14.0 | 57 | 1.27 |
| 27 | Corvin Moment | W Mich | JR | LB | 11 | 14.0 | 50 | 1.27 |
| 30 | Jack Sanborn | Wisconsin | SR | ILB | 10 | 12.5 | 49 | 1.25 |
| 30 | Arnold Ebiketie | Penn State | SR | DE | 8 | 10.0 | 48 | 1.25 |
| 32 | Clarence Hicks | UTSA | SR | OLB | 13 | 16.0 | 85 | 1.23 |
| 32 | KD Davis | N Texas | JR | LB | 13 | 16.0 | 63 | 1.23 |
| 34 | Mika Tafua | Utah | JR | DE | 9 | 11.0 | 66 | 1.22 |
| 34 | Kayvon Thibodeaux | Oregon | SO | DE | 9 | 11.0 | 57 | 1.22 |
| 34 | Jalen Pitre | Baylor | SR | S | 9 | 11.0 | 37 | 1.22 |
| 37 | Dante Stills | WVU | SR | DL | 10 | 12.0 | 58 | 1.20 |
| 37 | Felix Anudike-Uzomah | Kansas St | SO | DE | 10 | 12.0 | 51 | 1.20 |
| 39 | Josaiah Stewart | Coast Car | FR | DE | 13 | 15.5 | 85 | 1.19 |
| 40 | Cody Roscoe | Syracuse | SR | DL | 8 | 9.5 | 28 | 1.19 |
| 41 | Joe Ozougwu | Ark St | SR | DE | 11 | 13.0 | 60 | 1.18 |
| 42 | Nick Hampton | App St | JR | OLB | 12 | 14.0 | 75 | 1.17 |
| 42 | Jamal Hines | Toledo | JR | OLB | 12 | 14.0 | 59 | 1.17 |
| 42 | Myles Murphy | Clemson | SO | DE | 9 | 10.5 | 39 | 1.17 |
| 45 | Nik Bonitto | Oklahoma | JR | OLB | 10 | 11.5 | 54 | 1.15 |
| 45 | Drake Thomas | NC State | SO | LB | 10 | 11.5 | 30 | 1.15 |
| 47 | Micheal Clemons | Texas A&M | SR | DL | 7 | 8.0 | 39 | 1.14 |
| 47 | Garrett Nelson | Nebraska | SO | OLB | 7 | 8.0 | 36 | 1.14 |
| 49 | Charlie Thomas | Ga Tech | JR | LB | 8 | 9.0 | 36 | 1.13 |
| 49 | Brandon Smith | Penn State | JR | LB | 8 | 9.0 | 28 | 1.13 |
| 51 | Grayson Murphy | N Texas | FR | DE | 13 | 14.5 | 75 | 1.12 |
| 51 | DeAngelo Malone | Western Ky | SR | DE | 13 | 14.5 | 63 | 1.12 |
| 53 | BJ Ojulari | LSU | SO | DE | 9 | 10.0 | 58 | 1.11 |
| 53 | Tyree Wilson | Texas Tech | JR | DL | 9 | 10.0 | 53 | 1.11 |
| 53 | DeMarvin Leal | Texas A&M | JR | DL | 9 | 10.0 | 46 | 1.11 |
| 53 | Anfernee Orji | Vanderbilt | JR | LB | 9 | 10.0 | 35 | 1.11 |
| 57 | Tristan Nichols | Nevada | SR | DT | 10 | 11.0 | 66 | 1.10 |
| 57 | Isaiah Thomas | Oklahoma | SR | DL | 10 | 11.0 | 63 | 1.10 |
| 57 | Daniel Green | Kansas St | JR | LB | 10 | 11.0 | 33 | 1.10 |
| 60 | David Perales | Fresno St | SR | DE | 11 | 12.0 | 70 | 1.09 |
| 60 | Arron Mosby | Fresno St | SR | DE | 11 | 12.0 | 53 | 1.09 |
| 62 | Big Kat Bryant | UCF | SR | DL | 12 | 13.0 | 58 | 1.08 |
| 62 | Kameron Butler | Miami (Oh) | JR | DL | 12 | 13.0 | 58 | 1.08 |
| 64 | Mo Diallo | Arizona | SR | DL | 7 | 7.5 | 24 | 1.07 |
| 65 | Chris Ojoh | NMSU | JR | LB | 8 | 8.5 | 50 | 1.06 |
| 65 | Damone Clark | LSU | SR | LB | 8 | 8.5 | 23 | 1.06 |
| 65 | Branson Deen | Purdue | JR | DT | 8 | 8.5 | 21 | 1.06 |
| 68 | Trenton Simpson | Clemson | SO | LB | 9 | 9.5 | 50 | 1.06 |
| 68 | Zachary Carter | Florida | SR | DL | 9 | 9.5 | 45 | 1.06 |
| 70 | Brock Martin | Okla St | SR | DE | 10 | 10.5 | 48 | 1.05 |
| 70 | Aidan Hutchinson | Michigan | SR | DE | 10 | 10.5 | 44 | 1.05 |
| 72 | Kevin Atkins | Fresno St | SR | DT | 11 | 11.5 | 49 | 1.05 |
| 73 | Lonnie Phelps | Miami (Oh) | SO | DL | 12 | 12.5 | 69 | 1.04 |
| 73 | Karl Brooks | BGSU | JR | DL | 12 | 12.5 | 64 | 1.04 |
| 73 | Ben Kimpler | Miami (Oh) | SR | DL | 12 | 12.5 | 46 | 1.04 |
| 73 | James Patterson | Buffalo | SR | LB | 12 | 12.5 | 33 | 1.04 |
| 77 | Chauncey Manac | La-Lafytte | SR | LB | 14 | 14.5 | 87 | 1.04 |
| 78 | Praise Amaewhule | UTEP | SO | DE | 13 | 13.0 | 61 | 1.00 |
| 78 | Jonah Tavai | SDSU | SR | DL | 12 | 12.0 | 54 | 1.00 |
| 78 | Logan Hall | Houston | JR | DL | 12 | 12.0 | 49 | 1.00 |
| 78 | Desjuan Johnson | Toledo | JR | DE | 12 | 12.0 | 48 | 1.00 |
| 78 | Ivan Pace Jr. | Miami (Oh) | SO | LB | 12 | 12.0 | 44 | 1.00 |
| 78 | Calijah Kancey | Pittsburgh | SO | DL | 11 | 11.0 | 71 | 1.00 |
| 78 | Tre'mon Morris-Brash | UCF | JR | DL | 10 | 10.0 | 44 | 1.00 |
| 78 | Isaiah McGuire | Missouri | JR | DL | 10 | 10.0 | 40 | 1.00 |
| 78 | Chance Campbell | Miss | SR | LB | 10 | 10.0 | 39 | 1.00 |
| 78 | Hayden Henry | Arkansas | SR | LB | 10 | 10.0 | 37 | 1.00 |
| 78 | Myles Murphy | N Carolina | SO | DL | 9 | 9.0 | 31 | 1.00 |
| 78 | Tyrus Wheat | Miss St | SR | LB | 8 | 8.0 | 47 | 1.00 |
| 78 | Micah McFadden | Indiana | SR | LB | 7 | 7.0 | 34 | 1.00 |
| 78 | Theo Jackson | Tennessee | SR | DB | 7 | 7.0 | 19 | 1.00 |
| 78 | JoJo Domann | Nebraska | SR | OLB | 6 | 6.0 | 35 | 1.00 |
| 93 | Zach VanValkenburg | Iowa | SR | DL | 12 | 11.5 | 52 | 0.96 |
| 93 | Blake Carroll | Georgia St | SR | ILB | 12 | 11.5 | 40 | 0.96 |
| 93 | Justin Rice | Utah State | SR | ILB | 12 | 11.5 | 33 | 0.96 |
| 96 | Isaiah Foskey | Notre Dame | SO | DL | 11 | 10.5 | 107 | 0.96 |
| 96 | Jordan Jackson | Air Force | SR | DT | 11 | 10.5 | 76 | 0.96 |
| 98 | DeVere Levelston | SMU | JR | DE | 10 | 9.5 | 37 | 0.95 |
| 98 | Viliami Fehoko | SJSU | SO | DL | 10 | 9.5 | 33 | 0.95 |
| 100 | Derick Hall | Auburn | JR | EDG | 8 | 7.5 | 33 | 0.94 |
Note: To qualify, player must have played in 75% of his team's games.