2021 National Leaders Tackles For Loss - Games in November Only through 01/10/2022
| Name | Team | Yr | Pos | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Will Anderson Jr. | Alabama | SO | LB | 4 | 12.5 | 51 | 3.13 |
| 2 | Isaiah Gay | Illinois | SR | OLB | 3 | 8.0 | 28 | 2.67 |
| 3 | Josaiah Stewart | Coast Car | FR | DE | 4 | 10.5 | 60 | 2.63 |
| 4 | Vince Sanford | Air Force | JR | OLB | 4 | 9.0 | 47 | 2.25 |
| 4 | Scott Patchan | CSU | SR | DL | 4 | 9.0 | 47 | 2.25 |
| 6 | James Patterson | Buffalo | SR | LB | 3 | 6.5 | 15 | 2.17 |
| 7 | Damone Clark | LSU | SR | LB | 4 | 8.5 | 37 | 2.13 |
| 7 | Tre'mon Morris-Brash | UCF | JR | DL | 4 | 8.5 | 31 | 2.13 |
| 9 | Jamal Hines | Toledo | JR | OLB | 4 | 8.0 | 37 | 2.00 |
| 9 | Cameron Thomas | SDSU | JR | DL | 4 | 8.0 | 37 | 2.00 |
| 9 | Devin Lloyd | Utah | JR | LB | 4 | 8.0 | 32 | 2.00 |
| 9 | Daniel Green | Kansas St | JR | LB | 4 | 8.0 | 29 | 2.00 |
| 9 | Nik Bonitto | Oklahoma | JR | OLB | 3 | 6.0 | 29 | 2.00 |
| 14 | Chauncey Manac | La-Lafytte | SR | LB | 4 | 7.5 | 54 | 1.88 |
| 14 | Nick Heninger | Utah State | SR | DE | 4 | 7.5 | 53 | 1.88 |
| 16 | Mikel Jones | Syracuse | SO | LB | 3 | 5.5 | 23 | 1.83 |
| 17 | Jermaine Johnson II | FSU | SR | DE | 4 | 7.0 | 46 | 1.75 |
| 17 | Brenton Cox Jr. | Florida | JR | OLB | 4 | 7.0 | 41 | 1.75 |
| 17 | Andre Carter II | Army | JR | OLB | 4 | 7.0 | 41 | 1.75 |
| 17 | Chris Ojoh | NMSU | JR | LB | 4 | 7.0 | 35 | 1.75 |
| 17 | Rondell Bothroyd | Wk Forest | SO | DL | 4 | 7.0 | 33 | 1.75 |
| 17 | Aidan Hutchinson | Michigan | SR | DE | 4 | 7.0 | 32 | 1.75 |
| 17 | Cole Bishop | Utah | FR | S | 4 | 7.0 | 27 | 1.75 |
| 17 | Ivan Pace Jr. | Miami (Oh) | SO | LB | 4 | 7.0 | 25 | 1.75 |
| 17 | Joe Ozougwu | Ark St | SR | DE | 4 | 7.0 | 24 | 1.75 |
| 17 | Kameron Butler | Miami (Oh) | JR | DL | 4 | 7.0 | 23 | 1.75 |
| 17 | Darius Hodges | Tulane | FR | JOK | 4 | 7.0 | 19 | 1.75 |
| 17 | Drake Thomas | NC State | SO | LB | 4 | 7.0 | 9 | 1.75 |
| 29 | Storey Jackson | Liberty | SR | LB | 3 | 5.0 | 24 | 1.67 |
| 29 | Daymond Williams | Buffalo | JR | DT | 3 | 5.0 | 21 | 1.67 |
| 31 | Trenton Simpson | Clemson | SO | LB | 4 | 6.5 | 42 | 1.63 |
| 31 | Ali Fayad | W Mich | SR | DL | 4 | 6.5 | 31 | 1.63 |
| 31 | Darius Muasau | Hawai'i | JR | LB | 4 | 6.5 | 27 | 1.63 |
| 31 | Jaxon Player | Tulsa | SR | DL | 4 | 6.5 | 19 | 1.63 |
| 35 | Nick Anderson | Tulane | JR | LB | 4 | 6.0 | 36 | 1.50 |
| 35 | DQ Thomas | MTSU | SR | LB | 4 | 6.0 | 32 | 1.50 |
| 35 | Derick Hall | Auburn | JR | EDG | 4 | 6.0 | 29 | 1.50 |
| 35 | Calijah Kancey | Pittsburgh | SO | DL | 4 | 6.0 | 28 | 1.50 |
| 35 | Malcolm Rodriguez | Okla St | SR | LB | 4 | 6.0 | 27 | 1.50 |
| 35 | DeVere Levelston | SMU | JR | DE | 4 | 6.0 | 26 | 1.50 |
| 35 | Joey Noble | New Mexico | SR | DE | 4 | 6.0 | 25 | 1.50 |
| 35 | Terrel Bernard | Baylor | SR | LB | 4 | 6.0 | 24 | 1.50 |
| 35 | Jalen Pitre | Baylor | SR | S | 4 | 6.0 | 21 | 1.50 |
| 35 | Ralph Holley | W Mich | SR | DL | 4 | 6.0 | 16 | 1.50 |
| 35 | Perrion Winfrey | Oklahoma | SR | DL | 3 | 4.5 | 16 | 1.50 |
| 35 | Jalen Redmond | Oklahoma | SO | DL | 3 | 4.5 | 16 | 1.50 |
| 35 | Arron Mosby | Fresno St | SR | DE | 3 | 4.5 | 14 | 1.50 |
| 48 | Nick Hampton | App St | JR | OLB | 4 | 5.5 | 45 | 1.38 |
| 48 | Gabriel Murphy | N Texas | FR | DE | 4 | 5.5 | 33 | 1.38 |
| 48 | Arik Smith | Army | SR | LB | 4 | 5.5 | 32 | 1.38 |
| 48 | Arnold Ebiketie | Penn State | SR | DE | 4 | 5.5 | 31 | 1.38 |
| 48 | Jonah Tavai | SDSU | SR | DL | 4 | 5.5 | 28 | 1.38 |
| 48 | Devin Harper | Okla St | SR | LB | 4 | 5.5 | 26 | 1.38 |
| 48 | Sam Williams | Miss | SR | DL | 4 | 5.5 | 25 | 1.38 |
| 48 | Trajan Jeffcoat | Missouri | JR | DL | 4 | 5.5 | 20 | 1.38 |
| 48 | Leo Chenal | Wisconsin | JR | ILB | 4 | 5.5 | 20 | 1.38 |
| 48 | Jose Ramirez | EMU | SO | DL | 4 | 5.5 | 19 | 1.38 |
| 48 | Ben Kimpler | Miami (Oh) | SR | DL | 4 | 5.5 | 17 | 1.38 |
| 48 | Jack Sanborn | Wisconsin | SR | ILB | 4 | 5.5 | 15 | 1.38 |
| 48 | Mike Rose | Iowa State | SR | LB | 4 | 5.5 | 13 | 1.38 |
| 48 | Marcus Moore | Utah State | SR | DT | 4 | 5.5 | 11 | 1.38 |
| 48 | Gabe Reid | Stanford | SR | OLB | 4 | 5.5 | 8 | 1.38 |
| 63 | Durrell Johnson | Liberty | JR | DE | 3 | 4.0 | 16 | 1.33 |
| 63 | Brian Asamoah | Oklahoma | JR | LB | 3 | 4.0 | 16 | 1.33 |
| 63 | Walter Haire | BGSU | SR | DL | 3 | 4.0 | 7 | 1.33 |
| 66 | Demani Richardson | Texas A&M | JR | DB | 4 | 5.0 | 40 | 1.25 |
| 66 | Jordan Jackson | Air Force | SR | DT | 4 | 5.0 | 40 | 1.25 |
| 66 | Marcus Valdez | BC | SR | DE | 4 | 5.0 | 35 | 1.25 |
| 66 | Jacoby Windmon | UNLV | JR | ILB | 4 | 5.0 | 35 | 1.25 |
| 66 | Will McDonald IV | Iowa State | JR | DE | 4 | 5.0 | 30 | 1.25 |
| 66 | Mykol Clark | La Tech | FR | DL | 4 | 5.0 | 30 | 1.25 |
| 66 | Tyrus Wheat | Miss St | SR | LB | 4 | 5.0 | 30 | 1.25 |
| 66 | Josh Paschal | Kentucky | SR | DE | 4 | 5.0 | 29 | 1.25 |
| 66 | Owen Porter | Marshall | SO | DL | 4 | 5.0 | 28 | 1.25 |
| 66 | Dallas Turner | Alabama | FR | LB | 4 | 5.0 | 27 | 1.25 |
| 66 | Henry To'oTo'o | Alabama | JR | LB | 4 | 5.0 | 27 | 1.25 |
| 66 | Big Kat Bryant | UCF | SR | DL | 4 | 5.0 | 26 | 1.25 |
| 66 | Brock Martin | Okla St | SR | DE | 4 | 5.0 | 24 | 1.25 |
| 66 | Collin Oliver | Okla St | FR | DE | 4 | 5.0 | 24 | 1.25 |
| 66 | Zach VanValkenburg | Iowa | SR | DL | 4 | 5.0 | 23 | 1.25 |
| 66 | Dominique Robinson | Miami (Oh) | SR | DL | 4 | 5.0 | 22 | 1.25 |
| 66 | Dion Novil | N Texas | SR | DL | 4 | 5.0 | 22 | 1.25 |
| 66 | Daniel Joseph | NC State | SR | DL | 4 | 5.0 | 22 | 1.25 |
| 66 | Gabe Hall | Baylor | SO | DL | 4 | 5.0 | 21 | 1.25 |
| 66 | Dontae Wilson | Georgia St | SR | NG | 4 | 5.0 | 19 | 1.25 |
| 66 | Derek Parish | Houston | JR | DL | 4 | 5.0 | 19 | 1.25 |
| 66 | George Karlaftis | Purdue | JR | DE | 4 | 5.0 | 18 | 1.25 |
| 66 | Jontrey Hunter | Georgia St | JR | OLB | 4 | 5.0 | 17 | 1.25 |
| 66 | Bralen Trice | Washington | FR | OLB | 4 | 5.0 | 17 | 1.25 |
| 66 | Carson Wells | Colorado | JR | OLB | 4 | 5.0 | 16 | 1.25 |
| 66 | C.J. Brewer | Coast Car | SR | DT | 4 | 5.0 | 16 | 1.25 |
| 66 | Keir Thomas | FSU | SR | DE | 4 | 5.0 | 14 | 1.25 |
| 66 | William Kwenkeu | Temple | SR | LB | 4 | 5.0 | 13 | 1.25 |
| 66 | Kitan Oladapo | Oregon St | SO | DB | 4 | 5.0 | 12 | 1.25 |
| 66 | Leonard Taylor | Miami (Fl) | FR | DL | 4 | 5.0 | 11 | 1.25 |
| 66 | Tyler Grubbs | La Tech | FR | LB | 4 | 5.0 | 10 | 1.25 |
| 66 | Luke Masterson | Wk Forest | SR | LB | 4 | 5.0 | 9 | 1.25 |
| 66 | Jaylan Ford | Texas | SO | LB | 4 | 5.0 | 5 | 1.25 |
| 99 | David Perales | Fresno St | SR | DE | 3 | 3.5 | 33 | 1.17 |
| 99 | Alex Wright | UAB | JR | OLB | 3 | 3.5 | 27 | 1.17 |
Note: To qualify, player must have played in 75% of his team's games.