2021 Michigan State Spartans Opponent First Down Split Stats through 01/10/2022
| Split | G | Rush | Pass | Penalty | Total |
|---|---|---|---|---|---|
| All Games | 13 | 102 | 190 | 24 | 316 |
| at Home | 6 | 48 | 89 | 9 | 146 |
| on Road/Neutral Site | 7 | 54 | 101 | 15 | 170 |
| in Wins | 11 | 87 | 144 | 20 | 251 |
| in Losses | 2 | 15 | 46 | 4 | 65 |
| vs. Conference | 9 | 72 | 134 | 17 | 223 |
| vs. Non-Conference | 4 | 30 | 56 | 7 | 93 |
| vs. Ranked (AP) | 3 | 29 | 44 | 4 | 77 |
| vs. Unranked (AP) | 10 | 73 | 146 | 20 | 239 |
| vs. FBS (I-A) | 12 | 91 | 182 | 24 | 297 |
| vs. FCS (I-AA) | 1 | 11 | 8 | 0 | 19 |
| vs. FBS Winning | 8 | 53 | 140 | 16 | 209 |
| vs. FBS Non-Winning | 4 | 38 | 42 | 8 | 88 |
| vs. FBS Power 5 | 11 | 85 | 160 | 21 | 266 |
| vs. FBS non-Power 5 | 1 | 6 | 22 | 3 | 31 |
| in August/September | 4 | 38 | 51 | 5 | 94 |
| in October | 4 | 30 | 58 | 12 | 100 |
| in November | 4 | 26 | 75 | 7 | 108 |
| in December/January | 1 | 8 | 6 | 0 | 14 |