2010 Louisville Cardinals Opponent First Down Game Log through 01/10/2011
| Date | Opponent | Surface | Result | Rush | Pass | Penalty | Total |
|---|---|---|---|---|---|---|---|
| 09/04/10 | Kentucky | Turf | L 16-23 | 9 | 10 | 1 | 20 |
| 09/11/10 | Eastern Ky. | Turf | W 23-13 | 5 | 5 | 2 | 12 |
| 09/18/10 | @ Oregon St. | Turf | L 28-35 | 9 | 8 | 2 | 19 |
| 10/02/10 | @ Arkansas St. | Turf | W 34-24 | 10 | 7 | 2 | 19 |
| 10/09/10 | Memphis | Turf | W 56-0 | 3 | 9 | 1 | 13 |
| 10/15/10 | Cincinnati | Turf | L 27-35 | 9 | 11 | 2 | 22 |
| 10/23/10 | Connecticut | Turf | W 26-0 | 5 | 4 | 2 | 11 |
| 10/30/10 | @ Pittsburgh | Grass | L 3-20 | 6 | 8 | 1 | 15 |
| 11/06/10 | @ Syracuse | Turf | W 28-20 | 7 | 8 | 2 | 17 |
| 11/13/10 | South Fla. | Turf | L 21-24 | 6 | 3 | 1 | 10 |
| 11/20/10 | West Virginia | Turf | L 10-17 | 9 | 5 | 1 | 15 |
| 11/26/10 | @ Rutgers | Turf | W 40-13 | 11 | 10 | 2 | 23 |
| 12/21/10 | + Southern Miss. | Turf | W 31-28 | 10 | 10 | 4 | 24 |
| Totals | 99 | 98 | 23 | 220 | |||
| @ : Away, + : Neutral Site | |||||||