2016 Conference USA Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Charlotte | 4 | 134 | 651 | 4.86 | 9 | 33.50 | 162.75 |
| 2 | Marshall | 4 | 148 | 717 | 4.84 | 8 | 37.00 | 179.25 |
| 3 | Florida Atlantic | 4 | 168 | 984 | 5.86 | 16 | 42.00 | 246.00 |
| 4 | Southern Mississippi | 5 | 174 | 633 | 3.64 | 8 | 34.80 | 126.60 |
| 5 | UTEP | 4 | 182 | 873 | 4.80 | 10 | 45.50 | 218.25 |
| 6 | Florida International | 4 | 189 | 877 | 4.64 | 8 | 47.25 | 219.25 |
| 7 | Western Kentucky | 5 | 197 | 478 | 2.43 | 6 | 39.40 | 95.60 |
| 8 | Rice | 4 | 198 | 1196 | 6.04 | 12 | 49.50 | 299.00 |
| 9 | Old Dominion | 5 | 200 | 817 | 4.09 | 10 | 40.00 | 163.40 |
| 10 | Louisiana Tech | 5 | 204 | 889 | 4.36 | 11 | 40.80 | 177.80 |
| 11 | UTSA | 5 | 222 | 972 | 4.38 | 8 | 44.40 | 194.40 |
| 12 | Middle Tennessee | 5 | 239 | 1180 | 4.94 | 14 | 47.80 | 236.00 |
| 13 | North Texas | 5 | 262 | 1466 | 5.60 | 14 | 52.40 | 293.20 |