2016 Conference USA Leaders Passing Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 12 | 294 | 159 | 54.1 | 1998 | 6.8 | 16 | 9 | 123.01 | 24.5 | 166.5 |
| 2 | North Texas | 12 | 325 | 166 | 51.1 | 2387 | 7.3 | 20 | 13 | 125.09 | 27.1 | 198.9 |
| 3 | Marshall | 10 | 304 | 179 | 58.9 | 2347 | 7.7 | 14 | 7 | 134.32 | 30.4 | 234.7 |
| 4 | Rice | 11 | 320 | 202 | 63.1 | 3291 | 10.3 | 23 | 5 | 170.11 | 29.1 | 299.2 |
| 5 | UTEP | 12 | 346 | 210 | 60.7 | 2508 | 7.2 | 26 | 6 | 142.91 | 28.8 | 209.0 |
| 6 | UTSA | 13 | 408 | 224 | 54.9 | 2984 | 7.3 | 22 | 7 | 130.70 | 31.4 | 229.5 |
| 7 | Florida International | 12 | 366 | 226 | 61.7 | 2830 | 7.7 | 22 | 6 | 143.26 | 30.5 | 235.8 |
| 8 | Florida Atlantic | 12 | 355 | 233 | 65.6 | 3221 | 9.1 | 24 | 10 | 158.52 | 29.6 | 268.4 |
| 9 | Old Dominion | 13 | 418 | 245 | 58.6 | 2944 | 7.0 | 21 | 11 | 129.09 | 32.2 | 226.5 |
| 10 | Charlotte | 10 | 429 | 267 | 62.2 | 3030 | 7.1 | 19 | 15 | 129.20 | 42.9 | 303.0 |
| 11 | Middle Tennessee | 13 | 491 | 286 | 58.2 | 3260 | 6.6 | 24 | 11 | 125.68 | 37.8 | 250.8 |
| 12 | Western Kentucky | 13 | 516 | 303 | 58.7 | 3560 | 6.9 | 23 | 14 | 125.95 | 39.7 | 273.8 |
| 13 | Louisiana Tech | 14 | 494 | 323 | 65.4 | 3846 | 7.8 | 33 | 9 | 149.18 | 35.3 | 274.7 |