2016 Conference USA Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 12 | 1938 | 2244 | 697 | 4182 | 6.00 | 348.5 |
| 2 | Rice | 11 | 2423 | 3174 | 754 | 5597 | 7.42 | 508.8 |
| 3 | UTEP | 11 | 2387 | 2418 | 763 | 4805 | 6.30 | 436.8 |
| 4 | Marshall | 11 | 2374 | 2869 | 791 | 5243 | 6.63 | 476.6 |
| 5 | Florida Atlantic | 11 | 2802 | 2834 | 806 | 5636 | 6.99 | 512.4 |
| 6 | Charlotte | 11 | 1624 | 3396 | 817 | 5020 | 6.14 | 456.4 |
| 7 | Florida International | 12 | 2385 | 2830 | 823 | 5215 | 6.34 | 434.6 |
| 8 | UTSA | 12 | 1967 | 2842 | 835 | 4809 | 5.76 | 400.8 |
| 9 | Old Dominion | 12 | 1953 | 2726 | 836 | 4679 | 5.60 | 389.9 |
| 10 | North Texas | 12 | 2957 | 2529 | 891 | 5486 | 6.16 | 457.2 |
| 11 | Western Kentucky | 13 | 1275 | 3773 | 935 | 5048 | 5.40 | 388.3 |
| 12 | Louisiana Tech | 13 | 1891 | 3709 | 948 | 5600 | 5.91 | 430.8 |
| 13 | Middle Tennessee | 12 | 2491 | 3206 | 1017 | 5697 | 5.60 | 474.8 |