2016 Conference USA Leaders Opponent Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 2 | 21 | 195 | 10.5 | 97.5 |
| 2 | Marshall | 2 | 15 | 177 | 7.5 | 88.5 |
| 3 | Florida International | 2 | 17 | 159 | 8.5 | 79.5 |
| 4 | Middle Tennessee | 2 | 17 | 154 | 8.5 | 77.0 |
| 5 | Rice | 2 | 16 | 144 | 8.0 | 72.0 |
| 6 | Western Kentucky | 2 | 17 | 135 | 8.5 | 67.5 |
| 7 | Louisiana Tech | 2 | 15 | 130 | 7.5 | 65.0 |
| 7 | Southern Mississippi | 2 | 12 | 130 | 6.0 | 65.0 |
| 9 | UTEP | 1 | 10 | 115 | 10.0 | 115.0 |
| 10 | North Texas | 1 | 11 | 97 | 11.0 | 97.0 |
| 11 | Charlotte | 1 | 10 | 49 | 10.0 | 49.0 |
| 12 | UTSA | 2 | 5 | 45 | 2.5 | 22.5 |
| 13 | Old Dominion | 1 | 2 | 24 | 2.0 | 24.0 |