2016 Conference USA Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 2 | 1 | 11 | 12 | 6.00 |
| 2 | Marshall | 2 | 1 | 10 | 11 | 5.50 |
| 3 | Louisiana Tech | 2 | 2 | 5 | 7 | 3.50 |
| 3 | Western Kentucky | 2 | 1 | 6 | 7 | 3.50 |
| 3 | Middle Tennessee | 2 | 0 | 7 | 7 | 3.50 |
| 6 | Southern Mississippi | 2 | 2 | 4 | 6 | 3.00 |
| 6 | Rice | 2 | 1 | 5 | 6 | 3.00 |
| 6 | Florida International | 2 | 0 | 6 | 6 | 3.00 |
| 9 | North Texas | 1 | 1 | 4 | 5 | 5.00 |
| 10 | Florida Atlantic | 2 | 2 | 2 | 4 | 2.00 |
| 11 | Old Dominion | 1 | 0 | 2 | 2 | 2.00 |
| 12 | Charlotte | 1 | 1 | 0 | 1 | 1.00 |