2016 Conference USA Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2017
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 11 | 12 | 64 | 76 | 6.91 |
| 2 | Middle Tennessee | 10 | 10 | 56 | 66 | 6.60 |
| 3 | Charlotte | 10 | 13 | 49 | 62 | 6.20 |
| 4 | UTEP | 10 | 6 | 41 | 47 | 4.70 |
| 5 | Old Dominion | 11 | 10 | 40 | 50 | 4.55 |
| 5 | Louisiana Tech | 11 | 7 | 40 | 47 | 4.27 |
| 7 | Florida International | 10 | 6 | 39 | 45 | 4.50 |
| 8 | UTSA | 10 | 6 | 35 | 41 | 4.10 |
| 9 | Southern Mississippi | 10 | 8 | 34 | 42 | 4.20 |
| 9 | Marshall | 9 | 6 | 34 | 40 | 4.44 |
| 11 | North Texas | 11 | 12 | 30 | 42 | 3.82 |
| 12 | Rice | 9 | 2 | 29 | 31 | 3.44 |
| 13 | Florida Atlantic | 9 | 8 | 19 | 27 | 3.00 |