2016 Big 12 Conference Leaders Long All Purpose Plays - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Dede Westbrook | Oklahoma | SR | WR | 11 | 19 | 15 | 9 | 8 | 4 | 1 | 0 |
| 2 | Byron Pringle | Kansas St | SO | WR | 11 | 10 | 5 | 5 | 3 | 3 | 2 | 1 |
| 2 | James Washington | Okla St | JR | WR | 11 | 15 | 10 | 5 | 3 | 3 | 3 | 1 |
| 4 | Devin Duvernay | Texas | FR | WR | 10 | 4 | 4 | 3 | 3 | 2 | 1 | 0 |
| 4 | Joe Mixon | Oklahoma | SO | RB | 10 | 14 | 9 | 6 | 3 | 2 | 1 | 1 |
| 6 | Darius Anderson | TCU | FR | RB | 9 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 6 | Douglas Coleman | Texas Tech | FR | DB | 9 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 6 | Keke Coutee | Texas Tech | SO | WR | 10 | 11 | 3 | 3 | 2 | 1 | 1 | 0 |
| 6 | Jordan Evans | Oklahoma | SR | LB | 11 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 6 | D’Onta Foreman | Texas | JR | RB | 10 | 10 | 6 | 3 | 2 | 1 | 0 | 0 |
| 6 | Shelton Gibson | WVU | JR | WR | 11 | 13 | 8 | 5 | 2 | 1 | 0 | 0 |
| 6 | LaQuvionte Gonzalez | Kansas | JR | WR | 9 | 4 | 3 | 3 | 3 | 1 | 1 | 1 |
| 6 | Kene Nwangwu | Iowa State | FR | RB | 10 | 9 | 5 | 1 | 1 | 1 | 1 | 1 |
| 6 | Chris Platt | Baylor | SO | WR | 9 | 5 | 3 | 1 | 1 | 1 | 1 | 0 |
| 6 | D.J. Reed | Kansas St | SO | DB | 11 | 4 | 1 | 1 | 1 | 1 | 0 | 0 |
| 6 | Jhajuan Seales | Okla St | SR | WR | 11 | 6 | 3 | 2 | 1 | 1 | 1 | 0 |
| 6 | Quan Shorts | Texas Tech | FR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 6 | Justin Stockton | Texas Tech | JR | RB | 9 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 6 | Jacorey Warrick | Texas | SR | WR | 9 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 6 | Kris Williams | Texas Tech | SR | LB | 9 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 6 | Taj Williams | TCU | JR | WR | 11 | 4 | 3 | 2 | 2 | 1 | 0 | 0 |
| 6 | Ishmael Zamora | Baylor | SO | WR | 9 | 6 | 2 | 1 | 1 | 1 | 1 | 0 |