2016 Big 12 Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 11 | 13 | 194 | 0 | 1.18 |
| 1 | Kansas State | 11 | 13 | 190 | 3 | 1.18 |
| 3 | Texas | 10 | 10 | 101 | 0 | 1.00 |
| 3 | West Virginia | 11 | 10 | 65 | 0 | 0.91 |
| 5 | Oklahoma | 11 | 9 | 157 | 2 | 0.82 |
| 6 | Kansas | 9 | 8 | 131 | 1 | 0.89 |
| 7 | Baylor | 9 | 7 | 200 | 1 | 0.78 |
| 8 | TCU | 11 | 6 | 68 | 1 | 0.55 |
| 9 | Iowa State | 10 | 5 | 48 | 1 | 0.50 |
| 10 | Texas Tech | 10 | 3 | 15 | 0 | 0.30 |