2016 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. Ranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida State | 5 | 44 | 43 | 9 | 96 | 19.2 |
| 2 | Clemson | 7 | 53 | 65 | 20 | 138 | 19.7 |
| 3 | Duke | 3 | 38 | 22 | 2 | 62 | 20.7 |
| 4 | Miami (Florida) | 4 | 33 | 41 | 9 | 83 | 20.8 |
| 5 | North Carolina | 4 | 45 | 33 | 7 | 85 | 21.3 |
| 6 | Louisville | 3 | 25 | 32 | 9 | 66 | 22.0 |
| 7 | Wake Forest | 4 | 42 | 43 | 4 | 89 | 22.3 |
| 8 | Boston College | 4 | 36 | 45 | 11 | 92 | 23.0 |
| 9 | Virginia Tech | 2 | 16 | 24 | 7 | 47 | 23.5 |
| 10 | Georgia Tech | 3 | 31 | 39 | 1 | 71 | 23.7 |
| 11 | North Carolina State | 3 | 24 | 44 | 6 | 74 | 24.7 |
| 12 | Virginia | 3 | 35 | 35 | 5 | 75 | 25.0 |
| 13 | Syracuse | 6 | 68 | 79 | 5 | 152 | 25.3 |
| 14 | Pittsburgh | 4 | 19 | 79 | 9 | 107 | 26.8 |