2016 Atlantic Coast Conference Leaders Total Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 8 | 854 | 1098 | 511 | 1952 | 3.82 | 244.0 |
| 2 | Syracuse | 6 | 969 | 1414 | 434 | 2383 | 5.49 | 397.2 |
| 3 | Boston College | 9 | 568 | 1601 | 530 | 2169 | 4.09 | 241.0 |
| 4 | North Carolina | 9 | 2133 | 1609 | 695 | 3742 | 5.38 | 415.8 |
| 5 | Florida State | 8 | 780 | 1808 | 521 | 2588 | 4.97 | 323.5 |
| 6 | Miami (Florida) | 9 | 1070 | 1846 | 656 | 2916 | 4.45 | 324.0 |
| 7 | Wake Forest | 9 | 1148 | 1904 | 618 | 3052 | 4.94 | 339.1 |
| 8 | Louisville | 10 | 948 | 2056 | 695 | 3004 | 4.32 | 300.4 |
| 9 | North Carolina State | 10 | 1069 | 2076 | 660 | 3145 | 4.77 | 314.5 |
| 10 | Georgia Tech | 10 | 1765 | 2170 | 683 | 3935 | 5.76 | 393.5 |
| 11 | Virginia Tech | 12 | 1605 | 2237 | 825 | 3842 | 4.66 | 320.2 |
| 12 | Duke | 9 | 1380 | 2267 | 593 | 3647 | 6.15 | 405.2 |
| 13 | Virginia | 9 | 1635 | 2291 | 620 | 3926 | 6.33 | 436.2 |
| 14 | Pittsburgh | 9 | 1181 | 2473 | 664 | 3654 | 5.50 | 406.0 |