2016 Atlantic Coast Conference Leaders First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Clemson | 13 | 115 | 207 | 30 | 352 | 27.1 |
| 2 | Florida State | 11 | 116 | 124 | 24 | 264 | 24.0 |
| 3 | Virginia Tech | 11 | 107 | 137 | 19 | 263 | 23.9 |
| 3 | Wake Forest | 9 | 66 | 62 | 19 | 147 | 16.3 |
| 5 | Syracuse | 8 | 54 | 97 | 18 | 169 | 21.1 |
| 6 | Duke | 9 | 61 | 119 | 16 | 196 | 21.8 |
| 7 | Louisville | 10 | 113 | 108 | 15 | 236 | 23.6 |
| 7 | North Carolina State | 9 | 69 | 111 | 15 | 195 | 21.7 |
| 7 | North Carolina | 11 | 79 | 144 | 15 | 238 | 21.6 |
| 7 | Pittsburgh | 11 | 114 | 91 | 15 | 220 | 20.0 |
| 7 | Miami (Florida) | 9 | 63 | 102 | 15 | 180 | 20.0 |
| 12 | Virginia | 9 | 67 | 93 | 13 | 173 | 19.2 |
| 13 | Boston College | 9 | 50 | 53 | 12 | 115 | 12.8 |
| 14 | Georgia Tech | 11 | 130 | 46 | 11 | 187 | 17.0 |