2016 American Athletic Conference Leaders Interceptions - Games vs. Non-Conference Teams Only through 01/09/2017
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Parry Nickerson | Tulane | JR | CB | 4 | 2 | 133 | 1 | 0.50 |
| 2 | Jesse Brubaker | Tulsa | JR | DT | 5 | 2 | 90 | 2 | 0.40 |
| 3 | Tyrell Gilbert | Cincinnati | SO | S | 4 | 2 | 84 | 1 | 0.50 |
| 4 | Tajee Fullwood | S Florida | JR | CB | 5 | 2 | 69 | 1 | 0.40 |
| 5 | Kolton Shindelar | Tulsa | JR | DE | 5 | 1 | 65 | 1 | 0.20 |
| 6 | Jordan Wyatt | SMU | SO | DB | 4 | 3 | 62 | 1 | 0.75 |
| 7 | Jonathan Wilson | Memphis | FR | DL | 5 | 1 | 61 | 1 | 0.20 |
| 8 | Nigel Harris | S Florida | SR | LB | 5 | 1 | 49 | 0 | 0.20 |
| 9 | Delvon Randall | Temple | SO | DB | 5 | 3 | 36 | 0 | 0.60 |
| 10 | Horace Richardson | SMU | SR | DB | 4 | 3 | 31 | 0 | 0.75 |
| 11 | Genard Avery | Memphis | JR | LB | 5 | 1 | 28 | 1 | 0.20 |
| 12 | Mike Tyson | Cincinnati | SR | S | 3 | 3 | 27 | 0 | 1.00 |
| 13 | Darrion Millines | SMU | SR | DB | 4 | 2 | 26 | 0 | 0.50 |
| 13 | Jahmahl Pardner | Memphis | SR | DB | 4 | 1 | 26 | 0 | 0.25 |
| 15 | Drico Johnson | UCF | SR | DB | 5 | 1 | 25 | 0 | 0.20 |
| 16 | Rodney Clemons | SMU | FR | DB | 4 | 1 | 21 | 0 | 0.25 |
| 16 | Devin Abraham | S Florida | JR | S | 5 | 1 | 21 | 0 | 0.20 |
| 18 | Arthur Maulet | Memphis | SR | DB | 5 | 2 | 18 | 0 | 0.40 |
| 19 | Donnie Lewis Jr. | Tulane | SO | CB | 4 | 1 | 12 | 0 | 0.25 |
| 20 | Travon Simmons | ECU | JR | DB | 4 | 1 | 7 | 0 | 0.25 |
| 21 | Zach Edwards | Cincinnati | SR | S | 3 | 1 | 6 | 0 | 0.33 |