2016 American Athletic Conference Leaders Passes Defended - Games in August/September Only through 01/09/2017
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | 4 | 10 | 16 | 26 | 6.50 |
| 1 | SMU | 4 | 10 | 15 | 25 | 6.25 |
| 3 | Memphis | 3 | 7 | 11 | 18 | 6.00 |
| 4 | Tulsa | 4 | 4 | 22 | 26 | 6.50 |
| 4 | Houston | 5 | 4 | 17 | 21 | 4.20 |
| 4 | Tulane | 4 | 4 | 10 | 14 | 3.50 |
| 4 | Temple | 4 | 4 | 9 | 13 | 3.25 |
| 8 | South Florida | 4 | 3 | 12 | 15 | 3.75 |
| 9 | UCF | 4 | 2 | 22 | 24 | 6.00 |
| 10 | Connecticut | 5 | 1 | 14 | 15 | 3.00 |
| 10 | East Carolina | 4 | 1 | 10 | 11 | 2.75 |
| 12 | Navy | 3 | 0 | 6 | 6 | 2.00 |