2018 Conference USA Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 01/07/2019
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 4 | 25 | 0 | 24 | 0 | 0 | 174 | 43.5 |
| 2 | Southern Mississippi | 3 | 7 | 1 | 7 | 0 | 0 | 52 | 17.3 |
| 2 | Rice | 5 | 30 | 1 | 27 | 2 | 0 | 214 | 42.8 |
| 4 | Charlotte | 4 | 16 | 2 | 16 | 0 | 0 | 118 | 29.5 |
| 4 | Old Dominion | 4 | 19 | 2 | 18 | 0 | 0 | 138 | 34.5 |
| 6 | North Texas | 5 | 15 | 3 | 12 | 2 | 0 | 115 | 23.0 |
| 6 | Louisiana Tech | 5 | 19 | 3 | 17 | 0 | 0 | 140 | 28.0 |
| 8 | Middle Tennessee | 5 | 27 | 4 | 26 | 0 | 0 | 200 | 40.0 |
| 9 | UAB | 5 | 16 | 5 | 14 | 0 | 0 | 125 | 25.0 |
| 9 | UTEP | 4 | 17 | 5 | 16 | 0 | 0 | 133 | 33.3 |
| 9 | UTSA | 4 | 19 | 5 | 19 | 0 | 0 | 148 | 37.0 |
| 12 | Western Kentucky | 4 | 12 | 7 | 12 | 0 | 0 | 105 | 26.3 |
| 12 | Florida International | 5 | 16 | 7 | 15 | 1 | 0 | 134 | 26.8 |
| 14 | Marshall | 5 | 17 | 8 | 16 | 0 | 0 | 142 | 28.4 |