2018 Conference USA Leaders Opponent Penalties - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Old Dominion | 1 | 7 | 95 | 7.0 | 95.0 |
| 2 | Southern Mississippi | 1 | 9 | 78 | 9.0 | 78.0 |
| 3 | Florida International | 2 | 14 | 150 | 7.0 | 75.0 |
| 4 | North Texas | 1 | 10 | 70 | 10.0 | 70.0 |
| 4 | Florida Atlantic | 1 | 6 | 70 | 6.0 | 70.0 |
| 6 | UTSA | 3 | 22 | 206 | 7.3 | 68.7 |
| 7 | UTEP | 1 | 8 | 65 | 8.0 | 65.0 |
| 8 | Western Kentucky | 2 | 13 | 110 | 6.5 | 55.0 |
| 8 | Charlotte | 1 | 4 | 55 | 4.0 | 55.0 |
| 10 | Middle Tennessee | 3 | 20 | 154 | 6.7 | 51.3 |
| 11 | Louisiana Tech | 2 | 7 | 70 | 3.5 | 35.0 |
| 12 | Marshall | 2 | 8 | 66 | 4.0 | 33.0 |
| 13 | Rice | 2 | 6 | 51 | 3.0 | 25.5 |
| 14 | UAB | 1 | 1 | 15 | 1.0 | 15.0 |