2018 Big 12 Conference Leaders Interceptions - Games in August/September Only through 01/07/2019
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Kenny Robinson Jr. | WVU | SO | S | 4 | 2 | 55 | 0 | 0.50 |
| 1 | Shakial Taylor | Kansas | SR | CB | 5 | 1 | 55 | 1 | 0.20 |
| 3 | Adrian Frye | Texas Tech | FR | DB | 5 | 3 | 53 | 1 | 0.60 |
| 4 | Keith Washington Jr. | WVU | JR | CB | 4 | 1 | 51 | 1 | 0.25 |
| 5 | Bryce Torneden | Kansas | JR | S | 5 | 1 | 39 | 1 | 0.20 |
| 6 | Caden Sterns | Texas | FR | DB | 5 | 3 | 33 | 0 | 0.60 |
| 7 | Robert Barnes | Oklahoma | SO | S | 2 | 1 | 32 | 0 | 0.50 |
| 8 | Mike Lee | Kansas | JR | S | 5 | 1 | 31 | 1 | 0.20 |
| 9 | Terrel Bernard | Baylor | FR | LB | 5 | 1 | 28 | 0 | 0.20 |
| 10 | Devin Harper | Okla St | SO | LB | 5 | 1 | 24 | 1 | 0.20 |
| 11 | Elmore Hempstead Jr. | Kansas | JR | CB | 4 | 1 | 21 | 0 | 0.25 |
| 11 | Ridwan Issahaku | TCU | SR | S | 5 | 1 | 21 | 0 | 0.20 |
| 13 | Jarrick Bernard | Okla St | FR | S | 5 | 1 | 15 | 0 | 0.20 |
| 14 | Wyatt Hubert | Kansas St | FR | DE | 5 | 1 | 11 | 0 | 0.20 |
| 15 | Parnell Motley | Oklahoma | JR | CB | 5 | 2 | 7 | 0 | 0.40 |
| 15 | Brandon Jones | Texas | JR | DB | 4 | 1 | 7 | 0 | 0.25 |
| 17 | Kenneth Mann | Oklahoma | JR | DL | 4 | 1 | 6 | 0 | 0.25 |
| 18 | Jahron McPherson | Kansas St | SO | DB | 4 | 1 | 4 | 0 | 0.25 |
| 19 | Jeremiah McCullough | Kansas | JR | S | 5 | 1 | 1 | 0 | 0.20 |
| 19 | Joe Dineen Jr. | Kansas | SR | LB | 5 | 1 | 1 | 0 | 0.20 |