2018 Big 12 Conference Leaders Long All Purpose Plays - Games in November Only through 01/07/2019
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Jalen Reagor | TCU | SO | WR | 4 | 7 | 3 | 3 | 3 | 1 | 1 | 0 |
| 2 | Hakeem Butler | Iowa State | JR | WR | 4 | 5 | 4 | 4 | 2 | 1 | 1 | 0 |
| 3 | De'Quan Bowman | Texas Tech | SR | WR | 4 | 5 | 3 | 1 | 1 | 0 | 0 | 0 |
| 3 | Kennedy Brooks | Oklahoma | FR | RB | 4 | 3 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | Marquise Brown | Oklahoma | JR | WR | 4 | 6 | 4 | 2 | 1 | 0 | 0 | 0 |
| 3 | Vaughnte Dorsey | Texas Tech | SR | DB | 4 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Gary Jennings Jr. | WVU | SR | WR | 4 | 6 | 3 | 3 | 1 | 1 | 0 | 0 |
| 3 | CeeDee Lamb | Oklahoma | SO | WR | 4 | 3 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | John Lovett | Baylor | SO | RB | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Jeffrey McCulloch | Texas | JR | LB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Kyler Murray | Oklahoma | JR | QB | 4 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| 3 | Trey Sermon | Oklahoma | SO | RB | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | David Sills V | WVU | SR | WR | 4 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | Steven Sims Jr. | Kansas | SR | WR | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |