2018 Atlantic Coast Conference Leaders Passes Defended - Games in August/September Only through 01/07/2019
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 5 | 5 | 26 | 31 | 6.20 |
| 2 | Boston College | 5 | 8 | 25 | 33 | 6.60 |
| 3 | Wake Forest | 5 | 3 | 21 | 24 | 4.80 |
| 4 | Florida State | 5 | 6 | 19 | 25 | 5.00 |
| 5 | Virginia Tech | 4 | 4 | 18 | 22 | 5.50 |
| 6 | Miami (Florida) | 5 | 7 | 17 | 24 | 4.80 |
| 6 | North Carolina State | 4 | 4 | 17 | 21 | 5.25 |
| 8 | Duke | 5 | 3 | 16 | 19 | 3.80 |
| 9 | Georgia Tech | 5 | 7 | 14 | 21 | 4.20 |
| 10 | Pittsburgh | 5 | 3 | 13 | 16 | 3.20 |
| 11 | Syracuse | 5 | 8 | 12 | 20 | 4.00 |
| 11 | North Carolina | 4 | 1 | 12 | 13 | 3.25 |
| 11 | Clemson | 5 | 1 | 12 | 13 | 2.60 |
| 14 | Louisville | 5 | 2 | 11 | 13 | 2.60 |