2018 Atlantic Coast Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 10 | 12 | 52 | 64 | 6.40 |
| 2 | Clemson | 12 | 11 | 41 | 52 | 4.33 |
| 3 | Boston College | 9 | 12 | 38 | 50 | 5.56 |
| 4 | Pittsburgh | 11 | 5 | 43 | 48 | 4.36 |
| 5 | Miami (Florida) | 10 | 12 | 35 | 47 | 4.70 |
| 6 | North Carolina State | 9 | 6 | 39 | 45 | 5.00 |
| 7 | Florida State | 9 | 6 | 38 | 44 | 4.89 |
| 8 | Syracuse | 9 | 11 | 27 | 38 | 4.22 |
| 9 | North Carolina | 9 | 7 | 30 | 37 | 4.11 |
| 10 | Wake Forest | 8 | 2 | 32 | 34 | 4.25 |
| 11 | Duke | 10 | 3 | 26 | 29 | 2.90 |
| 12 | Georgia Tech | 10 | 7 | 20 | 27 | 2.70 |
| 13 | Virginia Tech | 8 | 4 | 20 | 24 | 3.00 |
| 14 | Louisville | 10 | 5 | 17 | 22 | 2.20 |