2018 American Athletic Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/07/2019
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UCF | 2 | 107 | 413 | 3.86 | 1 | 53.50 | 206.50 |
| 2 | Cincinnati | 1 | 36 | 134 | 3.72 | 2 | 36.00 | 134.00 |
| 2 | Tulsa | 1 | 47 | 241 | 5.13 | 2 | 47.00 | 241.00 |
| 4 | East Carolina | 2 | 93 | 563 | 6.05 | 4 | 46.50 | 281.50 |
| 5 | Tulane | 2 | 86 | 423 | 4.92 | 5 | 43.00 | 211.50 |
| 6 | SMU | 3 | 123 | 578 | 4.70 | 6 | 41.00 | 192.67 |
| 6 | Temple | 2 | 90 | 518 | 5.76 | 6 | 45.00 | 259.00 |
| 8 | South Florida | 2 | 110 | 629 | 5.72 | 7 | 55.00 | 314.50 |
| 9 | Houston | 1 | 58 | 507 | 8.74 | 8 | 58.00 | 507.00 |
| 10 | Memphis | 2 | 99 | 515 | 5.20 | 9 | 49.50 | 257.50 |
| 11 | Navy | 4 | 186 | 1035 | 5.56 | 13 | 46.50 | 258.75 |
| 12 | Connecticut | 4 | 180 | 1357 | 7.54 | 15 | 45.00 | 339.25 |