2018 American Athletic Conference Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 2 | 6 | 2 | 6 | 0 | 0 | 48 | 24.0 |
| 2 | Tulsa | 2 | 6 | 3 | 6 | 0 | 0 | 51 | 25.5 |
| 3 | UCF | 2 | 6 | 4 | 6 | 0 | 0 | 54 | 27.0 |
| 4 | South Florida | 2 | 6 | 5 | 6 | 0 | 0 | 57 | 28.5 |
| 5 | Tulane | 2 | 10 | 1 | 9 | 0 | 0 | 72 | 36.0 |
| 6 | Temple | 3 | 16 | 1 | 14 | 1 | 0 | 115 | 38.3 |
| 7 | East Carolina | 2 | 8 | 7 | 8 | 0 | 0 | 77 | 38.5 |
| 8 | Houston | 2 | 11 | 1 | 10 | 0 | 1 | 81 | 40.5 |
| 9 | SMU | 2 | 12 | 1 | 12 | 0 | 0 | 87 | 43.5 |
| 10 | Connecticut | 1 | 6 | 3 | 6 | 0 | 0 | 51 | 51.0 |
| 10 | Memphis | 2 | 13 | 4 | 12 | 0 | 0 | 102 | 51.0 |