2020 Big 12 Conference Leaders Long Rushing Plays - Games vs. FBS Teams With Winning Record Only through 01/11/2021
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Breece Hall | Iowa State | SO | RB | 8 | 20 | 8 | 5 | 3 | 3 | 3 | 2 | 0 | 0 |
| 1 | Bijan Robinson | Texas | FR | RB | 5 | 11 | 6 | 3 | 3 | 3 | 1 | 0 | 0 | 0 |
| 1 | SaRodorick Thompson | Texas Tech | SO | RB | 6 | 8 | 5 | 3 | 3 | 2 | 1 | 1 | 0 | 0 |
| 4 | Will Howard | Kansas St | FR | QB | 5 | 8 | 4 | 2 | 2 | 2 | 2 | 1 | 1 | 0 |
| 4 | Kene Nwangwu | Iowa State | SR | RB | 8 | 3 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| 6 | LD Brown | Okla St | SR | RB | 6 | 10 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 6 | Max Duggan | TCU | SO | QB | 5 | 8 | 5 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 6 | Velton Gardner | Kansas | SO | RB | 4 | 6 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 6 | Daniel Hishaw Jr. | Kansas | FR | RB | 5 | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 6 | Roschon Johnson | Texas | SO | RB | 6 | 4 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 6 | Marcus Major | Oklahoma | FR | RB | 4 | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 6 | Seth McGowan | Oklahoma | FR | RB | 4 | 5 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 6 | Rhamondre Stevenson | Oklahoma | SR | RB | 3 | 12 | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 6 | Xavier White | Texas Tech | SO | RB | 5 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |