2020 American Athletic Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 1 | 247 | 238 | 72 | 485 | 6.74 | 485.0 |
| 2 | Houston | 2 | 209 | 536 | 116 | 745 | 6.42 | 372.5 |
| 3 | Tulsa | 2 | 264 | 291 | 130 | 555 | 4.27 | 277.5 |
| 4 | South Florida | 2 | 481 | 233 | 138 | 714 | 5.17 | 357.0 |
| 5 | UCF | 2 | 441 | 685 | 154 | 1126 | 7.31 | 563.0 |
| 6 | Navy | 3 | 804 | 348 | 187 | 1152 | 6.16 | 384.0 |
| 7 | Cincinnati | 3 | 367 | 711 | 203 | 1078 | 5.31 | 359.3 |
| 8 | Memphis | 3 | 319 | 619 | 220 | 938 | 4.26 | 312.7 |
| 9 | SMU | 3 | 452 | 697 | 231 | 1149 | 4.97 | 383.0 |
| 10 | Tulane | 4 | 614 | 924 | 286 | 1538 | 5.38 | 384.5 |