2021 Conference USA Leaders Interceptions - Games Lost Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Teja Young | FAU | SO | S | 7 | 2 | 62 | 1 | 0.29 |
| 2 | Keondre Swoopes | UAB | JR | S | 4 | 1 | 61 | 1 | 0.25 |
| 3 | Jaiden Cole | La Tech | JR | DB | 8 | 2 | 57 | 0 | 0.25 |
| 4 | Quincy Riley | MTSU | FR | CB | 4 | 2 | 56 | 0 | 0.50 |
| 5 | Jay Stanley | USM | SO | DB | 9 | 1 | 55 | 1 | 0.11 |
| 6 | Ezekiel Barnett | La Tech | SR | LB | 9 | 1 | 46 | 0 | 0.11 |
| 7 | Romain Mungin | FAU | SO | CB | 5 | 1 | 40 | 0 | 0.20 |
| 8 | Micah Abraham | Marshall | SO | DB | 6 | 1 | 35 | 0 | 0.17 |
| 8 | Trey Baldwin | La Tech | SR | LB | 9 | 1 | 35 | 1 | 0.11 |
| 10 | Natrone Brooks | USM | JR | DB | 8 | 1 | 34 | 1 | 0.13 |
| 11 | Decorian Patterson | MTSU | SO | CB | 5 | 1 | 33 | 0 | 0.20 |
| 12 | Eric Scott, Jr. | USM | JR | DB | 9 | 2 | 23 | 0 | 0.22 |
| 12 | Harold West | N Texas | FR | DB | 7 | 1 | 23 | 0 | 0.14 |
| 14 | Dion Novil | N Texas | SR | DL | 7 | 1 | 17 | 0 | 0.14 |
| 15 | Roger Cray | ODU | SR | CB | 5 | 1 | 16 | 0 | 0.20 |
| 16 | R'Tarriun Johnson | ODU | JR | S | 7 | 2 | 15 | 0 | 0.29 |
| 16 | Naeem Smith | Rice | SR | S | 8 | 1 | 15 | 0 | 0.13 |
| 18 | Malik Shorts | USM | SO | DB | 9 | 2 | 13 | 0 | 0.22 |
| 19 | Kody Fulp | La Tech | JR | LB | 4 | 1 | 11 | 0 | 0.25 |
| 20 | Kirk Lockhart | Rice | SO | S | 7 | 1 | 10 | 0 | 0.14 |
| 21 | Luke Martin | Charlotte | SR | LB | 7 | 1 | 8 | 1 | 0.14 |
| 22 | Gabe Taylor | Rice | FR | DB | 8 | 2 | 6 | 0 | 0.25 |
| 23 | Dy'vonne Inyang | UTEP | SR | DB | 4 | 1 | 5 | 0 | 0.25 |
| 23 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 4 | 1 | 5 | 0 | 0.25 |