2021 Conference USA Leaders Passing Defense - On 3rd Down, 10+ Yards To Go through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Charlotte | 9 | 15 | 8 | 53.3 | 122 | 0 | 2 | 94.98 | 20 | 4 | 6 | 0 |
| 2 | UTEP | 13 | 39 | 13 | 33.3 | 141 | 0 | 2 | 53.44 | 34 | 6 | 6 | 1 |
| 3 | North Texas | 10 | 25 | 11 | 44.0 | 152 | 1 | 0 | 108.27 | 40 | 5 | 5 | 3 |
| 4 | Western Kentucky | 10 | 27 | 16 | 59.3 | 178 | 0 | 2 | 99.83 | 23 | 5 | 5 | 0 |
| 5 | Southern Mississippi | 11 | 33 | 22 | 66.7 | 231 | 1 | 3 | 117.29 | 41 | 5 | 6 | 2 |
| 6 | Old Dominion | 13 | 29 | 14 | 48.3 | 232 | 2 | 0 | 138.24 | 36 | 8 | 6 | 4 |
| 7 | Marshall | 12 | 36 | 17 | 47.2 | 244 | 2 | 1 | 116.93 | 64 | 6 | 4 | 2 |
| 8 | Florida Atlantic | 11 | 43 | 23 | 53.5 | 247 | 1 | 3 | 95.47 | 33 | 7 | 5 | 4 |
| 9 | Middle Tennessee | 12 | 38 | 16 | 42.1 | 248 | 1 | 2 | 95.09 | 48 | 6 | 5 | 5 |
| 10 | Rice | 9 | 24 | 13 | 54.2 | 258 | 0 | 2 | 127.80 | 65 | 6 | 8 | 1 |
| 11 | UTSA | 13 | 44 | 24 | 54.5 | 267 | 2 | 5 | 97.79 | 31 | 7 | 6 | 2 |
| 12 | UAB | 13 | 45 | 26 | 57.8 | 304 | 0 | 0 | 114.53 | 27 | 5 | 9 | 1 |
| 13 | Florida International | 9 | 23 | 16 | 69.6 | 305 | 3 | 0 | 224.00 | 74 | 11 | 8 | 3 |
| 14 | Louisiana Tech | 12 | 30 | 24 | 80.0 | 355 | 1 | 0 | 190.40 | 63 | 9 | 11 | 3 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||