2021 Conference USA Leaders Opponent First Downs - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 1 | 1 | 8 | 0 | 9 | 9.0 |
| 2 | Marshall | 1 | 3 | 4 | 2 | 9 | 9.0 |
| 2 | UTEP | 1 | 3 | 6 | 3 | 12 | 12.0 |
| 4 | UAB | 1 | 4 | 2 | 2 | 8 | 8.0 |
| 4 | Southern Mississippi | 1 | 4 | 5 | 0 | 9 | 9.0 |
| 4 | Rice | 1 | 4 | 14 | 3 | 21 | 21.0 |
| 7 | Florida International | 1 | 6 | 9 | 0 | 15 | 15.0 |
| 8 | Old Dominion | 1 | 7 | 5 | 1 | 13 | 13.0 |
| 8 | Louisiana Tech | 1 | 7 | 23 | 2 | 32 | 32.0 |
| 10 | UTSA | 1 | 8 | 1 | 1 | 10 | 10.0 |
| 11 | Charlotte | 1 | 9 | 4 | 1 | 14 | 14.0 |
| 11 | Western Kentucky | 1 | 9 | 9 | 4 | 22 | 22.0 |
| 13 | Middle Tennessee | 1 | 10 | 7 | 0 | 17 | 17.0 |
| 14 | North Texas | 1 | 11 | 8 | 2 | 21 | 21.0 |