2021 Conference USA Leaders Rushing Offense - On 1st Down through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Texas | 13 | 312 | 1440 | 4.62 | 13 | 75 | 40 | 40 | 11 |
| 2 | UTSA | 14 | 272 | 1254 | 4.61 | 10 | 81 | 29 | 29 | 6 |
| 3 | Rice | 12 | 233 | 1163 | 4.99 | 7 | 64 | 29 | 30 | 10 |
| 4 | UAB | 13 | 245 | 1114 | 4.55 | 11 | 43 | 34 | 37 | 11 |
| 5 | UTEP | 13 | 258 | 1072 | 4.16 | 6 | 74 | 32 | 33 | 6 |
| 6 | Marshall | 13 | 225 | 1002 | 4.45 | 12 | 41 | 29 | 31 | 7 |
| 7 | Florida Atlantic | 12 | 216 | 984 | 4.56 | 9 | 60 | 27 | 29 | 13 |
| 8 | Florida International | 12 | 204 | 915 | 4.49 | 6 | 68 | 22 | 24 | 5 |
| 9 | Old Dominion | 13 | 227 | 914 | 4.03 | 6 | 45 | 24 | 24 | 10 |
| 10 | Western Kentucky | 14 | 177 | 860 | 4.86 | 9 | 86 | 29 | 31 | 6 |
| 11 | Charlotte | 12 | 193 | 842 | 4.36 | 5 | 55 | 22 | 22 | 7 |
| 12 | Middle Tennessee | 13 | 221 | 761 | 3.44 | 8 | 65 | 26 | 26 | 6 |
| 13 | Southern Mississippi | 12 | 205 | 701 | 3.42 | 3 | 56 | 27 | 27 | 8 |
| 14 | Louisiana Tech | 12 | 203 | 584 | 2.88 | 7 | 22 | 17 | 17 | 3 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||