2021 Conference USA Leaders Rushing Offense - When Losing By 15+ Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UAB | 2 | 37 | 171 | 4.62 | 1 | 59 | 8 | 5 | 2 |
| 2 | North Texas | 5 | 145 | 648 | 4.47 | 4 | 75 | 37 | 22 | 2 |
| 3 | UTSA | 2 | 33 | 131 | 3.97 | 1 | 56 | 9 | 6 | 1 |
| 4 | Marshall | 3 | 21 | 80 | 3.81 | 2 | 16 | 5 | 4 | 0 |
| 5 | Old Dominion | 6 | 93 | 339 | 3.65 | 6 | 42 | 24 | 11 | 4 |
| 6 | UTEP | 4 | 47 | 165 | 3.51 | 1 | 45 | 9 | 5 | 1 |
| 7 | Rice | 6 | 116 | 406 | 3.50 | 3 | 23 | 22 | 13 | 3 |
| 8 | Florida Atlantic | 5 | 61 | 181 | 2.97 | 2 | 34 | 12 | 9 | 3 |
| 9 | Florida International | 9 | 101 | 222 | 2.20 | 2 | 25 | 13 | 7 | 2 |
| 10 | Charlotte | 5 | 63 | 135 | 2.14 | 2 | 13 | 12 | 6 | 0 |
| 10 | Louisiana Tech | 3 | 21 | 45 | 2.14 | 1 | 15 | 4 | 3 | 0 |
| 12 | Southern Mississippi | 7 | 93 | 189 | 2.03 | 0 | 19 | 12 | 5 | 0 |
| 13 | Western Kentucky | 3 | 24 | 48 | 2.00 | 1 | 14 | 6 | 2 | 0 |
| 14 | Middle Tennessee | 4 | 60 | 109 | 1.82 | 1 | 16 | 14 | 2 | 0 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||