2021 Conference USA Leaders Fumbles Lost - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | North Texas | 5 | 5 | 2 | 40.00 |
| 1 | Rice | 5 | 5 | 2 | 40.00 |
| 1 | Marshall | 6 | 8 | 2 | 25.00 |
| 4 | UTEP | 8 | 9 | 3 | 33.33 |
| 5 | Western Kentucky | 6 | 5 | 4 | 80.00 |
| 5 | Louisiana Tech | 5 | 7 | 4 | 57.14 |
| 5 | Middle Tennessee | 7 | 11 | 4 | 36.36 |
| 8 | UAB | 6 | 7 | 5 | 71.43 |
| 8 | Florida Atlantic | 5 | 10 | 5 | 50.00 |
| 8 | UTSA | 7 | 12 | 5 | 41.67 |
| 11 | Florida International | 6 | 7 | 6 | 85.71 |
| 11 | Old Dominion | 5 | 9 | 6 | 66.67 |
| 11 | Charlotte | 7 | 12 | 6 | 50.00 |
| 14 | Southern Mississippi | 6 | 11 | 8 | 72.73 |