2021 Conference USA Leaders Passing Offense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 1 | 44 | 26 | 59.1 | 341 | 7.8 | 3 | 2 | 137.60 | 44.0 | 341.0 |
| 2 | Western Kentucky | 1 | 65 | 46 | 70.8 | 488 | 7.5 | 3 | 0 | 149.07 | 65.0 | 488.0 |
| 3 | UTSA | 1 | 38 | 22 | 57.9 | 255 | 6.7 | 2 | 1 | 126.38 | 38.0 | 255.0 |
| 4 | UAB | 2 | 40 | 27 | 67.5 | 236 | 5.9 | 3 | 4 | 121.81 | 20.0 | 118.0 |
| 5 | Rice | 2 | 54 | 26 | 48.1 | 313 | 5.8 | 2 | 6 | 86.84 | 27.0 | 156.5 |
| 6 | Southern Mississippi | 1 | 24 | 11 | 45.8 | 131 | 5.5 | 2 | 1 | 110.85 | 24.0 | 131.0 |
| 7 | Marshall | 1 | 26 | 15 | 57.7 | 99 | 3.8 | 0 | 1 | 81.99 | 26.0 | 99.0 |
| 8 | Old Dominion | 1 | 38 | 18 | 47.4 | 127 | 3.3 | 1 | 2 | 73.60 | 38.0 | 127.0 |