2021 Conference USA Leaders Turnover Margin - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 13 | 10 | 21 | 31 | 7 | 12 | 19 | 12 | 0.92 |
| 2 | Middle Tennessee | 13 | 15 | 17 | 32 | 8 | 13 | 21 | 11 | 0.85 |
| 3 | Rice | 10 | 5 | 13 | 18 | 7 | 9 | 16 | 2 | 0.20 |
| 3 | Florida Atlantic | 12 | 6 | 13 | 19 | 11 | 8 | 19 | 0 | 0.00 |
| 5 | UTSA | 13 | 14 | 12 | 26 | 7 | 5 | 12 | 14 | 1.08 |
| 6 | Marshall | 12 | 8 | 10 | 18 | 9 | 14 | 23 | -5 | -0.42 |
| 6 | Southern Mississippi | 11 | 12 | 10 | 22 | 14 | 16 | 30 | -8 | -0.73 |
| 8 | UAB | 11 | 9 | 9 | 18 | 7 | 6 | 13 | 5 | 0.45 |
| 8 | Louisiana Tech | 11 | 13 | 9 | 22 | 7 | 14 | 21 | 1 | 0.09 |
| 10 | Charlotte | 12 | 6 | 8 | 14 | 10 | 10 | 20 | -6 | -0.50 |
| 10 | UTEP | 13 | 6 | 8 | 14 | 10 | 14 | 24 | -10 | -0.77 |
| 12 | Old Dominion | 12 | 8 | 7 | 15 | 9 | 12 | 21 | -6 | -0.50 |
| 13 | North Texas | 13 | 12 | 6 | 18 | 4 | 14 | 18 | 0 | 0.00 |
| 14 | Florida International | 12 | 6 | 3 | 9 | 10 | 12 | 22 | -13 | -1.08 |