2021 Conference USA Leaders Fumbles Lost - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | North Texas | 13 | 14 | 4 | 28.57 |
| 2 | UTSA | 13 | 19 | 7 | 36.84 |
| 3 | Middle Tennessee | 13 | 19 | 8 | 42.11 |
| 4 | Rice | 10 | 15 | 7 | 46.67 |
| 5 | Charlotte | 12 | 21 | 10 | 47.62 |
| 6 | Marshall | 12 | 18 | 9 | 50.00 |
| 6 | Old Dominion | 12 | 18 | 9 | 50.00 |
| 8 | Florida Atlantic | 12 | 21 | 11 | 52.38 |
| 9 | UTEP | 13 | 19 | 10 | 52.63 |
| 10 | UAB | 11 | 13 | 7 | 53.85 |
| 11 | Louisiana Tech | 11 | 12 | 7 | 58.33 |
| 11 | Western Kentucky | 13 | 12 | 7 | 58.33 |
| 13 | Florida International | 12 | 15 | 10 | 66.67 |
| 14 | Southern Mississippi | 11 | 20 | 14 | 70.00 |