2021 Conference USA Leaders Interceptions - Games in August/September Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 3 | 97 | 2 | 0.75 |
| 2 | Florida Atlantic | 4 | 5 | 25 | 1 | 1.25 |
| 2 | UAB | 4 | 4 | 87 | 1 | 1.00 |
| 2 | Middle Tennessee | 4 | 3 | 100 | 1 | 0.75 |
| 5 | Marshall | 4 | 3 | 70 | 0 | 0.75 |
| 5 | North Texas | 4 | 3 | 16 | 0 | 0.75 |
| 5 | Rice | 4 | 3 | 5 | 0 | 0.75 |
| 5 | UTEP | 4 | 2 | 51 | 0 | 0.50 |
| 5 | Southern Mississippi | 4 | 2 | 13 | 0 | 0.50 |
| 5 | Western Kentucky | 3 | 1 | 23 | 0 | 0.33 |
| 5 | Florida International | 4 | 1 | 0 | 0 | 0.25 |
| 5 | Charlotte | 4 | 1 | 0 | 0 | 0.25 |
| 5 | UTSA | 4 | 1 | 0 | 0 | 0.25 |