2021 Big 12 Conference Leaders Rushing - When Losing By 15+ Pts through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Devin Neal | Kansas | FR | RB | 7 | 46 | 232 | 5.04 | 0 | 21 | 13 | 8 | 1 |
| 2 | Jason Bean | Kansas | JR | QB | 6 | 23 | 136 | 5.91 | 1 | 34 | 9 | 5 | 1 |
| 3 | SaRodorick Thompson | Texas Tech | JR | RB | 4 | 25 | 109 | 4.36 | 2 | 24 | 5 | 2 | 2 |
| 4 | Bijan Robinson | Texas | SO | RB | 3 | 21 | 105 | 5.00 | 1 | 16 | 6 | 2 | 0 |
| 5 | Amauri Pesek-Hickson | Kansas | FR | RB | 6 | 32 | 100 | 3.13 | 0 | 12 | 8 | 2 | 0 |
| 6 | Caleb Williams | Oklahoma | FR | QB | 2 | 4 | 97 | 24.25 | 1 | 66 | 4 | 3 | 1 |
| 7 | Emari Demercado | TCU | SR | RB | 4 | 16 | 94 | 5.88 | 2 | 17 | 4 | 4 | 0 |
| 8 | Kennedy Brooks | Oklahoma | JR | RB | 2 | 11 | 93 | 8.45 | 1 | 65 | 2 | 1 | 1 |
| 9 | Xavier White | Texas Tech | JR | RB | 3 | 19 | 87 | 4.58 | 2 | 16 | 4 | 2 | 0 |
| 10 | Deuce Vaughn | Kansas St | SO | RB | 3 | 22 | 74 | 3.36 | 0 | 13 | 5 | 3 | 0 |
| 11 | Miles Kendrick | Kansas | SR | QB | 3 | 13 | 73 | 5.62 | 0 | 22 | 3 | 3 | 1 |
| 12 | Torry Locklin | Kansas | SO | WR | 6 | 21 | 64 | 3.05 | 1 | 12 | 1 | 1 | 0 |
| 13 | Garrett Greene | WVU | FR | QB | 2 | 12 | 55 | 4.58 | 1 | 13 | 4 | 3 | 0 |
| 14 | Leddie Brown | WVU | SR | RB | 4 | 15 | 54 | 3.60 | 1 | 20 | 1 | 2 | 1 |
| 15 | Casey Thompson | Texas | JR | QB | 2 | 9 | 47 | 5.22 | 3 | 9 | 1 | 0 | 0 |
| 16 | Joe Ervin | Kansas St | SO | RB | 2 | 5 | 40 | 8.00 | 0 | 13 | 2 | 1 | 0 |
| 16 | Spencer Sanders | Okla St | JR | QB | 2 | 5 | 40 | 8.00 | 0 | 12 | 5 | 3 | 0 |
| 18 | Breece Hall | Iowa State | JR | RB | 2 | 6 | 39 | 6.50 | 1 | 21 | 2 | 2 | 1 |
| 19 | Ahmonte Watkins | TCU | FR | RB | 2 | 10 | 35 | 3.50 | 0 | 25 | 3 | 2 | 1 |
| 20 | Kendre Miller | TCU | SO | RB | 2 | 13 | 34 | 2.62 | 0 | 8 | 2 | 0 | 0 |
| 21 | Chadarius Townsend | Texas Tech | SR | RB | 1 | 2 | 30 | 15.00 | 0 | 26 | 1 | 1 | 1 |
| 22 | Keilan Robinson | Texas | JR | RB | 2 | 9 | 27 | 3.00 | 0 | 8 | 2 | 0 | 0 |
| 22 | Chandler Morris | TCU | FR | QB | 2 | 10 | 27 | 2.70 | 0 | 8 | 2 | 0 | 0 |
| 24 | Myles Price | Texas Tech | SO | WR | 2 | 2 | 24 | 12.00 | 0 | 15 | 2 | 1 | 0 |
| 24 | Donovan Smith | Texas Tech | FR | QB | 3 | 9 | 24 | 2.67 | 1 | 10 | 0 | 1 | 0 |
| 26 | Eric Gray | Oklahoma | JR | RB | 1 | 4 | 23 | 5.75 | 0 | 15 | 1 | 1 | 0 |
| 27 | Erik Ezukanma | Texas Tech | JR | WR | 1 | 1 | 16 | 16.00 | 0 | 16 | 1 | 1 | 0 |
| 27 | Daimarqua Foster | TCU | SO | RB | 1 | 3 | 16 | 5.33 | 0 | 7 | 1 | 0 | 0 |
| 29 | Behren Morton | Texas Tech | FR | QB | 1 | 2 | 15 | 7.50 | 0 | 17 | 0 | 1 | 0 |
| 30 | Skylar Thompson | Kansas St | SR | QB | 1 | 3 | 14 | 4.67 | 1 | 11 | 1 | 1 | 0 |
| 31 | Hudson Card | Texas | FR | QB | 2 | 4 | 13 | 3.25 | 0 | 7 | 0 | 0 | 0 |
| 32 | Ben Sinnott | Kansas St | FR | FB | 1 | 1 | 9 | 9.00 | 0 | 9 | 1 | 0 | 0 |
| 32 | Dalton Rigdon | Texas Tech | SR | WR | 1 | 1 | 9 | 9.00 | 0 | 9 | 0 | 0 | 0 |
| 32 | Jaren Lewis | Kansas St | SO | QB | 1 | 3 | 9 | 3.00 | 0 | 8 | 1 | 0 | 0 |
| 35 | Henry Colombi | Texas Tech | SR | QB | 3 | 12 | 8 | 0.67 | 0 | 18 | 1 | 1 | 0 |
| 35 | Max Duggan | TCU | JR | QB | 3 | 14 | 8 | 0.57 | 0 | 10 | 2 | 1 | 0 |
| 37 | Taye Barber | TCU | SR | WR | 1 | 2 | 7 | 3.50 | 0 | 6 | 0 | 0 | 0 |
| 37 | Justin Johnson Jr. | WVU | FR | RB | 2 | 8 | 7 | 0.88 | 0 | 5 | 1 | 0 | 0 |
| 39 | Jirehl Brock | Iowa State | SO | RB | 2 | 3 | 5 | 1.67 | 0 | 5 | 0 | 0 | 0 |
| 40 | Trevor Wilson | Kansas | SO | WR | 1 | 1 | 4 | 4.00 | 0 | 4 | 0 | 0 | 0 |
| 40 | Brennan Presley | Okla St | SO | WR | 1 | 1 | 4 | 4.00 | 0 | 4 | 0 | 0 | 0 |
| 40 | Sam Jackson | TCU | FR | QB | 1 | 4 | 4 | 1.00 | 0 | 7 | 0 | 0 | 0 |
| 43 | Tony Mathis Jr. | WVU | SO | RB | 1 | 1 | 3 | 3.00 | 0 | 3 | 1 | 0 | 0 |
| 43 | Roschon Johnson | Texas | JR | RB | 1 | 1 | 3 | 3.00 | 0 | 3 | 0 | 0 | 0 |
| 43 | Jonathon Brooks | Texas | FR | RB | 1 | 1 | 3 | 3.00 | 0 | 3 | 0 | 0 | 0 |
| 46 | Velton Gardner | Kansas | JR | RB | 1 | 1 | 2 | 2.00 | 0 | 2 | 0 | 0 | 0 |
| 46 | Eli Sanders | Iowa State | FR | RB | 1 | 2 | 2 | 1.00 | 0 | 5 | 0 | 0 | 0 |
| 48 | Dezmon Jackson | Okla St | SR | RB | 1 | 2 | 1 | 0.50 | 0 | 1 | 0 | 0 | 0 |
| 48 | Tahj Brooks | Texas Tech | SO | RB | 2 | 4 | 1 | 0.25 | 0 | 2 | 1 | 0 | 0 |
| 50 | Phillip Brooks | Kansas St | JR | WR | 1 | 1 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | |||||||||||||