2021 Big 12 Conference Leaders Long Receiving Plays - Games in October Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Marvin Mims | Oklahoma | SO | WR | 5 | 14 | 6 | 6 | 6 | 2 | 1 | 0 | 0 | 0 |
| 1 | Xavier Worthy | Texas | FR | WR | 4 | 12 | 7 | 5 | 3 | 2 | 2 | 1 | 0 | 0 |
| 3 | Isaiah Esdale | WVU | SR | WR | 4 | 9 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Drew Estrada | Baylor | SR | WR | 4 | 6 | 3 | 3 | 2 | 1 | 0 | 0 | 0 | 0 |
| 3 | Keenan Garber | Kansas St | SO | WR | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Kaylon Geiger Sr. | Texas Tech | SR | WR | 5 | 8 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 3 | Xavier Hutchinson | Iowa State | SR | WR | 4 | 9 | 3 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Daniel Imatorbhebhe | Kansas St | SR | TE | 4 | 6 | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Sam James | WVU | JR | WR | 4 | 3 | 2 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 3 | Quentin Johnston | TCU | SO | WR | 4 | 12 | 7 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Kendre Miller | TCU | SO | RB | 5 | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Tarique Milton | Iowa State | SR | WR | 4 | 5 | 3 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | SaRodorick Thompson | Texas Tech | JR | RB | 5 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Tyquan Thornton | Baylor | SR | WR | 4 | 12 | 6 | 4 | 4 | 1 | 1 | 1 | 0 | 0 |
| 3 | Marcus Washington | Texas | JR | WR | 4 | 4 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Michael Woods II | Oklahoma | SR | WR | 3 | 5 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |