2021 Big 12 Conference Leaders All Purpose - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Trestan Ebner | Baylor | SR | RB | 2 | 53 | 27 | 22 | 67 | 21 | 169 | 8.0 | 84.5 |
| 2 | Malik Knowles | Kansas St | JR | WR | 1 | 4 | 42 | 0 | 36 | 5 | 82 | 16.4 | 82.0 |
| 3 | Brennan Presley | Okla St | SO | WR | 2 | 9 | 157 | 0 | 26 | 16 | 192 | 12.0 | 96.0 |
| 4 | Eric Gray | Oklahoma | JR | RB | 1 | 82 | 25 | 0 | 24 | 14 | 131 | 9.4 | 131.0 |
| 5 | Tyquan Thornton | Baylor | SR | WR | 2 | -11 | 73 | 0 | 18 | 9 | 80 | 8.9 | 40.0 |
| 6 | Jaylin Noel | Iowa State | FR | WR | 1 | 0 | 54 | 0 | 17 | 5 | 71 | 14.2 | 71.0 |
| 7 | Winston Wright Jr. | WVU | JR | WR | 1 | 0 | 16 | 0 | 11 | 4 | 27 | 6.8 | 27.0 |
| 8 | Graeson Malashevich | WVU | SO | WR | 1 | 0 | 0 | 0 | 5 | 1 | 5 | 5.0 | 5.0 |