2021 Big 12 Conference Leaders Tackles - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Malcolm Rodriguez | Okla St | SR | LB | 3 | 21 | 11 | 32 | 10.67 |
| 2 | Colin Schooler | Texas Tech | SR | LB | 2 | 12 | 2 | 14 | 7.00 |
| 3 | Devin Harper | Okla St | SR | LB | 3 | 11 | 9 | 20 | 6.67 |
| 3 | Jalen Pitre | Baylor | SR | S | 2 | 11 | 4 | 15 | 7.50 |
| 3 | Tanner McCalister | Okla St | SR | S | 3 | 11 | 0 | 11 | 3.67 |
| 6 | Kolby Harvell-Peel | Okla St | SR | S | 3 | 10 | 9 | 19 | 6.33 |
| 7 | Jarrick Bernard-Converse | Okla St | SR | CB | 3 | 9 | 1 | 10 | 3.33 |
| 7 | Christian Holmes | Okla St | SR | CB | 3 | 9 | 1 | 10 | 3.33 |
| 7 | Daniel Green | Kansas St | JR | LB | 1 | 9 | 0 | 9 | 9.00 |
| 10 | Jayden Jernigan | Okla St | SO | DT | 3 | 8 | 2 | 10 | 3.33 |
| 10 | Jabbar Muhammad | Okla St | SO | CB | 3 | 8 | 1 | 9 | 3.00 |
| 12 | Terrel Bernard | Baylor | SR | LB | 2 | 7 | 7 | 14 | 7.00 |
| 12 | Delarrin Turner-Yell | Oklahoma | SR | S | 1 | 7 | 3 | 10 | 10.00 |
| 12 | Wyatt Harris | TCU | JR | LB | 1 | 7 | 2 | 9 | 9.00 |
| 12 | Krishon Merriweather | Texas Tech | SR | LB | 2 | 7 | 2 | 9 | 4.50 |
| 16 | DeMarvion Overshown | Texas | SR | LB | 2 | 6 | 11 | 17 | 8.50 |
| 16 | Dillon Doyle | Baylor | JR | LB | 2 | 6 | 7 | 13 | 6.50 |
| 16 | Jesiah Pierre | Texas Tech | SO | LB | 2 | 6 | 3 | 9 | 4.50 |
| 16 | Devin Drew | Texas Tech | SR | DL | 2 | 6 | 2 | 8 | 4.00 |
| 16 | Tyler Lacy | Okla St | JR | DE | 3 | 6 | 2 | 8 | 2.67 |
| 16 | Tre'Vius Hodges-Tomlinson | TCU | JR | CB | 1 | 6 | 1 | 7 | 7.00 |
| 16 | Jason Taylor II | Okla St | JR | S | 3 | 6 | 1 | 7 | 2.33 |
| 16 | T.J. Carter | TCU | SR | S | 1 | 6 | 0 | 6 | 6.00 |
| 24 | Reggie Pearson Jr. | Texas Tech | JR | DB | 2 | 5 | 4 | 9 | 4.50 |
| 24 | D'Shawn Jamison | Texas | SR | DB | 2 | 5 | 3 | 8 | 4.00 |
| 24 | Kyron Johnson | Kansas | SR | DE | 1 | 5 | 2 | 7 | 7.00 |
| 24 | JT Woods | Baylor | SR | S | 2 | 5 | 2 | 7 | 3.50 |
| 24 | Riko Jeffers | Texas Tech | SR | LB | 2 | 5 | 2 | 7 | 3.50 |
| 24 | DaMarcus Fields | Texas Tech | SR | DB | 2 | 5 | 0 | 5 | 2.50 |
| 30 | Luke Brockermeyer | Texas | JR | LB | 2 | 4 | 12 | 16 | 8.00 |
| 30 | Brock Martin | Okla St | SR | DE | 3 | 4 | 6 | 10 | 3.33 |
| 30 | Ricky Thomas Jr. | Kansas | SR | S | 1 | 4 | 4 | 8 | 8.00 |
| 30 | Brandon Bouyer-Randle | Texas Tech | SR | LB | 2 | 4 | 4 | 8 | 4.00 |
| 30 | Gavin Potter | Kansas | JR | LB | 1 | 4 | 2 | 6 | 6.00 |
| 30 | D.J. Graham | Oklahoma | SO | CB | 1 | 4 | 2 | 6 | 6.00 |
| 30 | TJ Franklin | Baylor | JR | DL | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Raleigh Texada | Baylor | SR | CB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Matt Jones | Baylor | SO | LB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Eric Monroe | Texas Tech | SR | DB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Rayshad Williams | Texas Tech | JR | DB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | David Gbenda | Texas | SO | LB | 2 | 4 | 2 | 6 | 3.00 |
| 30 | Korie Black | Okla St | SO | CB | 3 | 4 | 2 | 6 | 2.00 |
| 30 | David Ugwoegbu | Oklahoma | JR | LB | 1 | 4 | 1 | 5 | 5.00 |
| 30 | Ochaun Mathis | TCU | JR | DE | 1 | 4 | 1 | 5 | 5.00 |
| 30 | Thomas Harper | Okla St | JR | S | 2 | 4 | 1 | 5 | 2.50 |
| 30 | Ray Thornton | Texas | SR | EDG | 2 | 4 | 1 | 5 | 2.50 |
| 30 | Russ Yeast | Kansas St | SR | DB | 1 | 4 | 0 | 4 | 4.00 |
| 30 | Terrell Cooper | TCU | SR | DT | 1 | 4 | 0 | 4 | 4.00 |
| 30 | Jacob Morgenstern | Texas Tech | SR | LB | 2 | 4 | 0 | 4 | 2.00 |
| 50 | Ovie Oghoufo | Texas | JR | EDG | 2 | 3 | 9 | 12 | 6.00 |