2021 Big 12 Conference Leaders Scoring Defense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Baylor | 8 | 17 | 10 | 16 | 0 | 0 | 148 | 18.5 |
| 2 | Kansas State | 6 | 18 | 12 | 18 | 0 | 0 | 162 | 27.0 |
| 3 | Oklahoma | 6 | 22 | 5 | 20 | 1 | 0 | 169 | 28.2 |
| 4 | Iowa State | 7 | 24 | 7 | 23 | 0 | 0 | 188 | 26.9 |
| 5 | Oklahoma State | 9 | 24 | 7 | 23 | 0 | 1 | 190 | 21.1 |
| 6 | Texas Tech | 7 | 24 | 8 | 23 | 0 | 1 | 193 | 27.6 |
| 7 | West Virginia | 8 | 25 | 15 | 24 | 1 | 0 | 221 | 27.6 |
| 8 | Texas | 8 | 29 | 19 | 25 | 1 | 0 | 258 | 32.3 |
| 9 | TCU | 7 | 40 | 5 | 38 | 1 | 0 | 295 | 42.1 |
| 10 | Kansas | 7 | 43 | 6 | 43 | 0 | 0 | 319 | 45.6 |