2021 Big 12 Conference Leaders Opponent First Downs - Games Won Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Kansas | 2 | 16 | 24 | 4 | 44 | 22.0 |
| 2 | Iowa State | 7 | 48 | 51 | 5 | 104 | 14.9 |
| 3 | TCU | 5 | 34 | 46 | 6 | 86 | 17.2 |
| 3 | Texas | 5 | 40 | 47 | 6 | 93 | 18.6 |
| 5 | Kansas State | 8 | 48 | 67 | 10 | 125 | 15.6 |
| 5 | West Virginia | 6 | 41 | 44 | 10 | 95 | 15.8 |
| 7 | Texas Tech | 7 | 37 | 86 | 11 | 134 | 19.1 |
| 8 | Oklahoma | 11 | 80 | 134 | 15 | 229 | 20.8 |
| 9 | Oklahoma State | 12 | 60 | 105 | 21 | 186 | 15.5 |
| 10 | Baylor | 12 | 81 | 111 | 26 | 218 | 18.2 |