2021 Big 12 Conference Leaders Rushing Offense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 9 | 292 | 1616 | 5.53 | 20 | 32.44 | 179.56 |
| 2 | Oklahoma | 9 | 297 | 1517 | 5.11 | 16 | 33.00 | 168.56 |
| 3 | Texas | 9 | 333 | 1656 | 4.97 | 14 | 37.00 | 184.00 |
| 4 | TCU | 9 | 355 | 1736 | 4.89 | 14 | 39.44 | 192.89 |
| 5 | Baylor | 10 | 396 | 1831 | 4.62 | 17 | 39.60 | 183.10 |
| 6 | Kansas State | 9 | 274 | 1251 | 4.57 | 15 | 30.44 | 139.00 |
| 7 | Texas Tech | 9 | 299 | 1296 | 4.33 | 19 | 33.22 | 144.00 |
| 8 | Oklahoma State | 10 | 448 | 1919 | 4.28 | 21 | 44.80 | 191.90 |
| 9 | Kansas | 9 | 316 | 1211 | 3.83 | 10 | 35.11 | 134.56 |
| 10 | West Virginia | 9 | 316 | 1115 | 3.53 | 10 | 35.11 | 123.89 |