2021 Big 12 Conference Leaders Interceptions - Games Lost Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 2 | 3 | 32 | 0 | 1.50 |
| 1 | Baylor | 2 | 3 | 7 | 0 | 1.50 |
| 3 | Iowa State | 6 | 5 | 40 | 1 | 0.83 |
| 4 | TCU | 7 | 5 | 52 | 0 | 0.71 |
| 4 | Texas | 7 | 5 | 49 | 0 | 0.71 |
| 6 | West Virginia | 7 | 4 | 1 | 0 | 0.57 |
| 7 | Kansas | 10 | 5 | 115 | 1 | 0.50 |
| 8 | Kansas State | 5 | 2 | 0 | 0 | 0.40 |
| 9 | Texas Tech | 6 | 1 | 0 | 0 | 0.17 |